摘要
Abstract
Objective To analyze the effect of Liraglutide combined with Metformin in the treatment of diabetes combined with obesity.Methods From January 2022 to January 2023,70 patients with diabetes combined with obesity admitted to the Department of Endocrinology of Liaoning Health Industry Group Iron Coal General Hospital were selected as research sub-jects.According to random number table method,they were divided into conventional group(35 cases)and study group(35 cases).The conventional group was treated with Metformin alone,the study group was treated with Liraglutide combined with Metformin.Adverse reactions,blood glucose levels,body mass index(BMI),inflammatory factors and intestinal flora levels were compared between the two groups.Results The incidence of adverse reactions in the study group was lower than that in the conventional group,the difference was statistically significant(P＜0.05).The blood glucose level and BMI of the study group were lower than those of the conventional group,and the differences were statistically significant(P＜0.05).The levels of inflammatory factors in the study group were lower than those in the conventional group,and the differences were statisti-cally significant(P＜0.05).The bifidobacteria and bacteroides in the study group were higher than those in the conventional group,and the enterobacteria and enterococcus were lower than those in the conventional group,with statistical significances(P＜0.05).Conclusion Liraglutide combined with Metformin should be used for the treatment of diabetes combined with obesity.This treatment can improve the level of intestinal flora,blood sugar and BMI of patients,reduce the level of inflam-matory factors and the incidence of adverse reactions in patients,and the application effect is very significant.关键词
利拉鲁肽/二甲双胍/糖尿病/肥胖症/效果/分析Key words
Liraglutide/Metformin/Diabetes/Obesity/Effect/Analysis分类
医药卫生
