吉林中医药2023，Vol.43Issue(12)：1438-1441,4.DOI:10.13463/j.cnki.jlzyy.2023.12.018
湿热困脾型2型糖尿病合并非酒精性脂肪肝的危险因素
Clinical study on main risk factors for the syndrome of dampness-heat retaining in the spleen in T2DM patients complicated with NAFLD
摘要
Abstract
Objective To investigate the main risk factors for the syndrome of dampness-heat retaining in the spleen in type 2 diabetes mellitus(T2DM)patients complicated with nonalcoholic fatty liver disease(NAFLD).Methods From June 2018 to June 2020,300 T2DM patients with the syndrome of dampness-heat retaining in the spleen in our hospital were divided into a fatty liver group and a non-fatty liver group for the presence of NAFLD.The body mass index(BMI),aspartate transaminase(AST),alanine transaminase(ALT),gamma-glutamyl transferase(GGT),alkaline phosphatase(ALP),high-density lipoprotein cholesterol(HDL-C),serum uric acid(SUA),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),total cholesterol(TC),fasting C-peptide(FC-P),serum fasting insulin(FINS),insulin resistance(IR)and fasting blood glucose(FBG)were compared between the two groups.Results The single factor analysis showed that the levels of BMI,IR,liver hardness,spleen hardness,spleen thickness,GGT,ALP,SUA,TG,TC,LDL-C,FBG of T2DM complicated with NAFLD were significantly higher than those of the non-fatty liver group(all P＜0.05),while the levels of HDL-C and FINS were significantly lower than those of the non-fatty liver group(P＜0.05).The multivariate analysis showed that BMI and IR were the risk factors for T2DM patients with NAFLD(P＜0.05).Conclusion BMI and IR are the main risk factors for the syndrome of dampness-heat retaining in the spleen in T2DM patients complicated with NAFLD.关键词
2型糖尿病/非酒精性脂肪肝/湿热困脾型/瞬时弹性成像Key words
type 2 diabetes/nonalcoholic fatty liver disease/syndrome of dampness-heat retaining in spleen/transient elastography分类
临床医学引用本文复制引用
祁月英,王笑,季璇,武慧敏,吴进,张忠勇..湿热困脾型2型糖尿病合并非酒精性脂肪肝的危险因素[J].吉林中医药,2023,43(12):1438-1441,4.基金项目
河北省中医药管理局项目(2018479) （2018479）
