临床输血与检验2023，Vol.25Issue(6)：802-805,4.DOI:10.3969/j.issn.1671-2587.2023.06.015
冰点冷却倒置离心法降低冰冻血浆乳糜程度的研究
The effect of freezing point cooling Inverted centrifugation method on frozen plasma chylemia reduction
摘要
Abstract
Objective The aim of this study is to explore the efficiency of freezing point cooling inverted centrifugation on plasma chylemia reduction.Methods 46 bags of frozen plasma(200 mL/bag)were collected from blood composition preparation process.The freezing point cooling inverted centrifugation was employed for removal of chylemia from plasma,and the absorbance,lipid levers,total plasma protein(TP)and chylemia were analyzed before or after the centrifugation to evaluate the effect of chylemia reduction.Results After the treatment of freezing point cooling inverted centrifugation,the OD value,TG content and chylous index of were significantly decreased in moderate chylous plasma(P＜0.01).While,the levels of TC,HDL,LDL and TP were not significantly different from those without treatment(P＞0.05).The OD value,TG content and chylous index were significantly decreased in severe chylous plasma after treatment of freezing point cooling inverted centrifugation(P＜0.01).The appearance of plasma was significant improved,and the compliance rate of comprehensive standards was 75%.However,the levels of TC,HDL,LDL and TP were not significantly different from those without treatment(P＞0.05).Conclusion Freezing point cooling inverted centrifugation method can effectively reduce plasma chyle degree,improve the compliance rate of plasma quality control,reduce the scrap rate of blood and minimize the waste of blood resources as much as possible.关键词
血浆/乳糜程度/冰点冷却倒置离心法Key words
Plasma/Chyle degree/Freezing point cooling inverted centrifugation method分类
医药卫生引用本文复制引用
平娜娜,张雅莉,兰静,张卫..冰点冷却倒置离心法降低冰冻血浆乳糜程度的研究[J].临床输血与检验,2023,25(6):802-805,4.基金项目
本项目受中国输血协会团体标准基金(No.P2020-003)、西安市科技计划项目基金(No.21YXYJ0087)资助 （No.P2020-003）
