摘要
Abstract
Objective To analyze the incidence of vascular calcification and its influencing factors in elderly patients with diabetic nephropathy undergoing maintenance hemodialysis,and provide evidence for its prevention and treatment.Methods The general data,imaging data and laboratory indicators of 138 elderly patients with diabetic nephropathy who un-derwent maintenance hemodialysis in Jiaozhou Central Hospital of Qingdao City from February 2020 to February 2022 were ana-lyzed retrospectively.The incidence of vascular calcification in these patients was analyzed according to their imaging diagnosis results.According to whether the patients had vascular calcification or not,they were divided into calcification group and non-calcification group.The influencing factors of vascular calcification were analyzed by univariate analysis and multiple logistic regression analysis.Results Among 138 elderly patients with diabetic nephropathy undergoing maintenance hemodialysis,93 ones(67.39%)had vascular calcification(calcification group)and 45 ones(32.61%)had no vascular calcification(non-calcification group).There was no statistically significant difference in gender,body mass index(BMI),abdominal circum-ference,coronary heart disease,mean arterial pressure,triglyceride,serum albumin and 25-hydroxyvitamin D between the two groups(P＞0.05),while there were statistically significant differences in age,dialysis time,blood phosphorus,blood calcium and high-sensitivity C-reactive protein between the two groups(P＜0.05).Multivariate logistic regression analysis showed that increasing age,prolonged dialysis time,elevated blood calcium level and elevated hypersensitive C-reactive protein level were the influential factors for vascular calcification in elderly patients with diabetic nephropathy undergoing maintenance hemodialy-sis(P＜0.05).Conclusion The incidence of vascular calcification is higher in elderly patients with diabetic nephropathy un-dergoing maintenance hemodialysis.Its influencing factors may include increasing age,prolonged dialysis time,elevated blood calcium level and elevated hypersensitive C-reactive protein level.Therefore,clinical attention should be paid to these influen-cing factors and early prevention and treatment measures should be taken.关键词
老年/糖尿病肾病/维持性血液透析/血管钙化/影响因素Key words
elderly/diabetic nephropathy/maintenance hemodialysis/vascular calcification/influencing factor
