皮肤性病诊疗学杂志2023，Vol.30Issue(6)：495-501,7.DOI:10.3969/j.issn.1674-8468.2023.06.003
修护舒缓功效性护肤品在改善敏感肌中的应用:基于60例队列研究
Application of tone repair skincare product in the improvement of sensitive skin:Based on a cohort study of 60 cases
摘要
Abstract
Objective To explore the role of functional skincare products in improving sensi-tive skin.Methods A total of 60 subjects with sensitive skin were selected by lactic acid sting test and randomly divided into the treated and control groups,30 subjects per group.The treated group used tone repair skincare product and the untreated group served as the controls.The im-provements in skin hydration,transepidermal water loss,a*value,redness area,and investiga-tors'and subjects'self-evaluation scores were compared between the two groups 2 hours and 28 days after the applications.Results Compared to the control group,28-day applications of tone repair skincare product significantly improved lactic acid sting scores(Z=-2.83,P＜0.05).The stratum corneum hydration levels were increased both 2 hours and 28 days after topical appli-cations of the products.In contrast,transepidermal water loss rates were dramatically decreased after 28-day applications(P＜0.05,vs.controls).Both a*value and proportion of redness area were markedly decreased 2 hours after application of the product(P＜0.05 for both).However,no significant differences in a*value and proportion of redness area were observed between the treated and control groups after 28-day applications.The investigators'assessment showed signifi-cant improvements in sensitive skin symptoms and sign,such as dryness,scales,telangiectasia and skin tightness in the treatment group compared to the control group(P＜0.05).Conclusions Functional skincare products can improve the skin barrier function,playing an important role in improving the physiological state of sensitive skin.关键词
功效性护肤品/皮肤屏障功能/敏感肌/修护Key words
functional skincare products/skin barrier function/sensitive skin/repair引用本文复制引用
廖志刚,文思,冼雪松,王北明,龚俊瑞,张柏慧,梁锦茵,傅小晏,叶理..修护舒缓功效性护肤品在改善敏感肌中的应用:基于60例队列研究[J].皮肤性病诊疗学杂志,2023,30(6):495-501,7.基金项目
南方医科大学皮肤病医院-华润三九联合实验室华润顺峰基金重点项目(HR202103) （HR202103）
南方医科大学皮肤病医院-华润三九联合实验室华润顺峰基金苗圃项目(HR202110) （HR202110）
