皮肤性病诊疗学杂志2023，Vol.30Issue(6)：518-523,6.DOI:10.3969/j.issn.1674-8468.2023.06.006
环钻切除术联合CO2点阵激光治疗凹陷型痤疮瘢痕的临床效果
Therapeutic effect of trephine resection combined with fractional ablative CO2 laser in the treatment of pitted acne scars
摘要
Abstract
Objective To evaluate the efficacy and safety of trephine resection combined with fractional ablative CO2 laser for pitted acne scars.Methods Sixty eight patients with facial pitted acne scars were enrolled from the Medical Cosmetology Center of Zhengzhou People's Hospital from February 2019 to February 2022.The patients were randomly divided into the observation(30 patients)and the control groups(38 patients).The observation group was treated with tre-phine resection combined with CO2 laser,and the control group was treated with fractional ablative CO2 laser alone.The efficacy and the ECCA scale(Echelle d'Evaluation Clinique des Cicatrices d acne)were compared between the two groups after 6-month treatment.Results Before the treat-ment,ECCA scores were comparable between the observation and the control groups[50.00(43.75,60.00)vs.47.50(37.50,60.00),P=0.535].After 6-month treatment,the ECCA scores in both groups were significantly lower than the baseline(both P＜0.01),and the ECCA scores were significantly lower in the observation group[20.00(15.00,30.00)]than in the con-trols[25.00(20.00,30.00)](P=0.032).The effective rate in the observation group was sig-nificantly higher than that in the controls(93.33％vs.71.05％,P=0.020).But adverse reac-tions did not differ significantly between the two groups(P=1.000).Conclusions Trephine re-section combined with fractional ablative CO2 laser is more effective than fractional ablative CO2 la-ser alone for facial pitted acne scars and is safe.关键词
环钻切除术/点阵激光/凹陷型痤疮瘢痕/痤疮Key words
trephine resection/fractional ablative laser/pitted acne scar/acne引用本文复制引用
张艳红,黄玉成,许慧,陈晓昱,刘一萌,范晓盼,孙林林..环钻切除术联合CO2点阵激光治疗凹陷型痤疮瘢痕的临床效果[J].皮肤性病诊疗学杂志,2023,30(6):518-523,6.基金项目
河南省医学科技攻关计划项目(LHGJ20210744) （LHGJ20210744）
