皮肤性病诊疗学杂志2023，Vol.30Issue(6)：524-528,5.DOI:10.3969/j.issn.1674-8468.2023.06.007
黄褐斑发病机制研究进展
Insights in the development in the pathogenesis of melasma
摘要
Abstract
The pathogenesis of melasma is complicated.Genetic predisposition,female sex hormone and photoaging play predominant roles in melasma.While the current research in this field has focused on the effects of female sex hormone and ultraviolet on the melanogenesis,mela-nin transportation and distribution through paracrine regulation by keratinocytes,fibroblasts and vascular endothelial cells,the role of dermal extracellular matrix in hyperpigmentation is becoming the new hot spot.The important research area in the future will be to determine how genetic pre-disposition,female sex hormone and photoaging synergistically contribute to the development of melasma.关键词
黄褐斑/遗传易感性/雌性激素/光老化Key words
melasma/genetic predisposition/female sex hormone/photoaging引用本文复制引用
许庆芳,欧阳梦婷..黄褐斑发病机制研究进展[J].皮肤性病诊疗学杂志,2023,30(6):524-528,5.基金项目
国家自然科学基金(81773340) （81773340）
广东省自然科学基金(2021A1515012622 （）
2022A1515012451) （）
