皮肤性病诊疗学杂志2023，Vol.30Issue(6)：534-538,5.DOI:10.3969/j.issn.1674-8468.2023.06.009
IL-17与痤疮相关性的研究进展
Advances in the study of the association between IL-17 and acne
段忆雪 1温炬 1秦思 1黄文彬 1李慕锦1
作者信息
- 1. 暨南大学附属广东省第二人民医院,广东 广州 510317
- 折叠
摘要
Abstract
Acne is a chronic inflammatory disease involving the sebaceous unit of hair follicles,with a complex pathogenesis.Currently,it is believed that the pathogenesis of acne is related to androgen levels,excessive sebum secretion,hyperkeratosis of hair follicles,C.acnes and others.In recent years,studies have revealed the pathogenic role of a variety of inflammatory factors in ac-ne,among which IL-17 is highly expressed in the epidermis and serum of acne patients,and its levels are positively correlated with the severity of acne,becoming a biomarker for early diagnosis of acne.A large amount of evidence indicates the involvement of IL-17 in the pathogenesis of ac-ne,possibly playing a dominant role.IL-17 is involved in the inflammatory cascade of various ac-ne,thereby changing severity of inflammation.But the specific mechanisms are not clear.This ar-ticle reviews the research progress of the correlation between IL-17 and acne,and discusses the anti-inflammatory and therapeutic effects of anti-IL-7 on acne,in order to determine the pathogen-ic role of IL-17 in acne.关键词
痤疮/IL-17/IL-17A/痤疮丙酸杆菌Key words
acne/IL-17/IL-17A/C.acnes引用本文复制引用
段忆雪,温炬,秦思,黄文彬,李慕锦..IL-17与痤疮相关性的研究进展[J].皮肤性病诊疗学杂志,2023,30(6):534-538,5.
