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上海市崇明区老年人群白蛋白尿的影响因素分析

王娟 顾红霞 杨婕 石群 秦利

老年医学与保健2023,Vol.29Issue(6):1298-1301,1307,5.
老年医学与保健2023,Vol.29Issue(6):1298-1301,1307,5.

上海市崇明区老年人群白蛋白尿的影响因素分析

Analysis of influencing factors of albuminuria in elderly population in Chongming district of Shanghai city

王娟 1顾红霞 1杨婕 1石群 1秦利1

作者信息

  • 1. 上海健康医学院附属崇明医院内分泌科,上海 202150
  • 折叠

摘要

Abstract

Objective To explore the influencing factors of albuminuria in elderly population in Chongming district of Shanghai city.Methods From May 2011 to October 2011,a random cluster sampling was conducted among the residents of Chengqiao Town,Chongming District,Shanghai.According to urinary microalbumin/urinary creatinine ratio(UACR)≥30 mg/g,473 subjects were included in albuminuria group.A propensity score of 1∶3 was used to match 1 419 subjects in the normal group.Their age,gender,body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),waist-to-hip ratio(WHR)were recorded.Their total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),fasting blood glucose(FBG),postprandial 2-hour blood glucose(2 hPBG),glycated hemoglobin(HbA1c),blood uric acid(UA)and estimated glomerular filtration rate(eGFR)were measured.The correlation analysis was used to analyze the correlation between each factor and UACR,and binary logistic re-gression was used to analyze the influencing factors of UACR.Results Compared with the normal group,the levels of BMI,SBP,DBP,TG,LDL-C,FBG,2 hPBG,HbA1c and UA of the albuminuria group were higher,and the level of eGFR was low-er,with statistical significances(P<0.05).Correlation analysis showed that BMI,SBP,DBP,TG,LDL-C,FBG,2 hPBG,HbA1c and UA were positively correlated with UACR,and eGFR was negatively correlated with UACR(P<0.05).Binary logistic regression analysis showed that BMI≥28 kg·m-2 and elevated SBP,LDL-C and FBG were risk factors for UACR,while elevated eGFR was a protective factor for UACR.Conclusion BMI≥28 kg·m-2,elevated SBP,LDL-C,FBG,and decreased eGFR may be influencing factors for albuminuria in the elderly population in Chongming district of Shanghai city.

关键词

老年人/糖代谢/脂代谢/尿微量白蛋白/尿肌酐比值/影响因素

Key words

elderly/glucose metabolism/lipid metabolism/urinary microalbumin/urine creatinine ratio/influencing factor

引用本文复制引用

王娟,顾红霞,杨婕,石群,秦利..上海市崇明区老年人群白蛋白尿的影响因素分析[J].老年医学与保健,2023,29(6):1298-1301,1307,5.

基金项目

上海市崇明区科委"可持续发展科技创新行动计划"(CKY2018-22) (CKY2018-22)

老年医学与保健

OACSTPCD

1008-8296

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