环境与职业医学2023，Vol.40Issue(12)：1370-1378,9.DOI:10.11836/JEOM23223
郑州市大气污染与精神疾病日门诊量的关系
Relationship between air pollution and daily psychiatric outpatient visits in Zhengzhou
摘要
Abstract
[Background]Psychiatric diseases are a serious threat to human health.Studies have shown an association between ambient air pollution and psychiatric diseases,yet the results are inconsistent. [Objective]To explore the potential effects of air pollution exposure on psychiatric diseases using Zhengzhou City as an example. [Methods]Outpatient consultation data of the Clinical Psychology Clinic at The First Affiliated Hospital of Henan University of Traditional Chinese Medicine as well as air quality data between 28 October 2013 and 28 August 2019 were collected.The exposure-lag effect between air pollutant exposure and daily outpatient visits was assessed using a distribution lag nonlinear model(DLNM),and subgroup analyses were conducted including sex(male and female),age(<18,18-59,and>59 years),season(spring,summer,autumn,and winter),and types of diseases(depression and anxiety). [Results]A total of 112986 valid confirmed outpatient visit records for psychiatric diseases were collected.The largest proportions of visits in each subgroup were females,18-59 years old,spring,and depression.The results of one-day lagged risk of total outpatient visits showed that PM2.5,PM10,SO2,and NO2 all significantly associated with an increased risk of psychiatric outpatient visits.The one-day lagged risk peaks were:PM2.5(RR=1.0016,95%CI:1.0011,1.0022),PM10(RR=1.0012,95%CI:1.0001,1.0022),SO2(RR=1.0060,95%CI:1.0002,1.0117),and NO2(RR=1.0144,95%CI:1.0100,1.0187).The cumulative lagged risk peaks were:PM2.5(CumRR=1.0274,95%CI:1.0158,1.0392),PM10(CumRR=1.0124,95%CI:1.0044,1.0205),SO2(CumRR=1.0214,95%CI:1.0009,1.0423),and NO2(CumRR=1.0613,95%CI:1.0460,1.0770).The results of subgroup analysis showed more significant impacts of air pollution exposure on females and people aged 18-59 years,and in winter.To be specific,PM2.5(RR=1.0022,95%CI:1.0006,1.0037),PM10(RR=1.0015,95%CI:1.0003,1.0027),SO2(RR=1.0082,95%CI:1.0016,1.0148),and NO2(RR=1.0156,95%CI:1.0106,1.0206)exposures associated with an increased risk of outpatient visits for psychiatric disorders in women;PM2.5(RR=1.0018,95%CI:1.0011,1.0024),PM10(RR=1.0012,95%CI:1.0001,1.0023),and NO2(RR=1.0142,95%CI:1.0095,1.0189)associated with an increased risk of visits in those 18-59 years of age;PM2.5(RR= 1.0043,95%CI:1.0001,1.0085),PM10(RR= 1.0038,95%CI:1.0007,1.0069),and NO2(RR= 1.0215,95%CI:1.0117,1.0313)in winter months significantly associated with an increased risk of psychiatric outpatient visits.In addition,the risk of depression and anxiety visits varied depending on the concentration of air pollutants and the duration of exposure.The risk of visits for depression were more affected by CO,NO2,and SO2,and the risk of visits for anxiety were more affected by PM2.5,PM10,and O3. [Conclusion]Exposure to air pollution is associated with an increased risk of psychiatric outpatient visits.The effects vary by air pollutants as well as by sex,age,type of psychiatric illness,and season.关键词
大气污染物/精神疾病/非线性滞后分布模型/相对风险值/性别/年龄/季节Key words
air pollutants/psychiatric illness/non-linear lagged distribution model/relative risk/sex/age/season分类
医药卫生引用本文复制引用
孔德琪,王炎,黄慧敏,马宁怡,千孟丹,李亚..郑州市大气污染与精神疾病日门诊量的关系[J].环境与职业医学,2023,40(12):1370-1378,9.基金项目
国家自然科学基金面上项目(82274495,82074403) （82274495,82074403）
河南省中医药科学研究专项课题(20-21ZY1019) （20-21ZY1019）
河南省特色骨干学科中医学学科建设项目(STG-ZYXKY-2020014) （STG-ZYXKY-2020014）
