皮肤性病诊疗学杂志2023，Vol.30Issue(6)：561-566,6.DOI:10.3969/j.issn.1674-8468.2023.06.015
DNA甲基化在紫外线相关皮肤病中的研究进展
Update on DNA methylation in UV radiation-related skin diseases
摘要
Abstract
DNA methylation is a common epigenetic phenomenon that changes genetic expres-sion without altering the DNA sequence.With deepening research on DNA methylation,more and more variable positions of methylation have been identified in a variety of diseases(such as tumors,diabetes and neurological disorders).Ultraviolet(UV)radiation is an important environmental factor for skin damage and aging.DNA methylation is involved in the occurrence and development of UV radiation-related skin conditions and diseases.In this paper,we review the research pro-gress of DNA methylation in UV radiation-related skin diseases,such as solar dermatitis,actinic keratosis,skin tumor,lupus erythematosus and photoaging,in order to provide new ideas for sub-sequent research in UV radiation-related skin diseases.关键词
DNA甲基化/表观遗传学/日光性皮炎/光化性角化病/光老化Key words
DNA methylation/epigenetics/solar dermatitis/actinic keratosis/pho-toaging引用本文复制引用
陈雯婷,钟欣妮,李巍..DNA甲基化在紫外线相关皮肤病中的研究进展[J].皮肤性病诊疗学杂志,2023,30(6):561-566,6.基金项目
国家自然科学基金(81301380) （81301380）
