临床输血与检验2023，Vol.25Issue(6)：749-752,4.DOI:10.3969/j.issn.1671-2587.2023.06.006
静脉输注丙种球蛋白对非新生儿溶血患儿交叉配血的影响
The Effect of Intravenous Immunoglobulin on Cross-match in Non-neonatal Hemolytic Children
陈旭升 1杨永涛1
作者信息
- 1. 清华大学第一附属医院输血科,北京 100016
- 折叠
摘要
Abstract
Objective To study the effect of intravenous immunoglobulin(IVIG)on cross-match in non-hemolytic anemia in children to discuss the best-practice transfusion strategy.Methods A total of 12 non-ABO hemolytic patients with negative antibody screening and cross-match incompatibility from January 2020 to December 2022 were included.Blood type identification was performed by tube test method.Antibody screening,cross-match,direct antiglobulin test(DAT),and anti-A and anti-B detection in free plasma and elution test were performed by microcolumn gel card method.Results After receiving IVIG,anti-A was detected in 6 type A and 2 type AB,anti-B in 3 type B,and anti-A and anti-B in 1 type AB.All patients were DAT positive,and appeared different degrees of hemolysis.Those were cross-match incompatible with same blood type suspended red blood cells,but cross-match compatible with type O washed red blood cells.Conclusion After administration of IVIG,some non-ABO hemolysis children have cross-match incompatibility and mild hemolytic symptoms,so it is advisable to choose O-type washed red blood cell.关键词
静脉注射丙种球蛋白/溶血性输血反应/交叉配血不合Key words
Intravenous immunoglobulin/Hemolytic transfusion reaction/Cross-match incompatibility引用本文复制引用
陈旭升,杨永涛..静脉输注丙种球蛋白对非新生儿溶血患儿交叉配血的影响[J].临床输血与检验,2023,25(6):749-752,4.
