江苏省农村癫痫患者苯巴比妥治疗的疗效分析OACSTPCD

Objective:To evaluate the efficacy of phenobarbital monotherapy on epilepsy in rural areas of Jiangsu Province.Methods:The convulsive epilepsy cases were treated with phenobarbital drugs and follow-up management from January 2005 to December 2020.The clinical characteristics,dosage,curative efficacy,and adverse reactions of epilepsy patients were evaluated.Results:A total of 4 315 patients with convulsive seizures were included,and 73.8%of the patients had a maximum phenobarbital dosage ranging from 30 to 90 mg/d.2 715 patients were followed up for four years,and the effective rate of treatment was 75.44%,with approximately 20%of patients experiencing deterioration of epilepsy symptoms.The incidence of adverse reactions such as fatigue,dizziness,and headache decreased from 16.2%(1st month)to 10.87%(4th year).Conclusion:The phenobarbital monotherapy for convulsive epilepsy patients achieved good clinical efficacy,and can be further promoted and implemented in rural areas.