药学研究2023,Vol.42Issue(12):1010-1015,6.DOI:10.13506/j.cnki.jpr.2023.12.011
巨噬细胞极化在糖尿病性创面愈合中的作用及药物研究进展
The role of macrophage polarization in diabetic wounds and the progress of drug research
摘要
Abstract
Macrophage is one of the most important immune cells in human body environment.Macrophage has high plasticity,M1 type(classical activated macrophage)can be transformed into M2 type(substitute activated macrophage)under different stimulation.There are many ways to promote the healing of diabetic wounds,such as regulating insulin resist-ance,regulating inflammation and promoting vascular repair.From the perspective of macrophages as participants in wound healing.The paper reviewed the research progress of macrophage polarization in promoting the mechanism of diabetic wound healing in recent years,providing corresponding reference for the treatment of diabetic wound in the future.关键词
巨噬细胞极化/糖尿病性创面/创面修复/药物研究Key words
Macrophage/Diabetic wound/Wound repair/Drug research分类
医药卫生引用本文复制引用
李杰辉,梁彬,王丽..巨噬细胞极化在糖尿病性创面愈合中的作用及药物研究进展[J].药学研究,2023,42(12):1010-1015,6.基金项目
国家自然科学基金资助项目(No.82360931) (No.82360931)
广西中医药大学2023年校级博士研究生科研创新项目(No.YCBXJ2023003) (No.YCBXJ2023003)
广西科技重点研发计划项目(No.桂科AB17292046) (No.桂科AB17292046)