生命科学仪器2023，Vol.21Issue(4)：9-17,9.DOI:10.11967/2023210802
小胶质细胞在太空飞行导致的认知障碍中的作用
The role of microglia in spaceflight-induced cognitive impairment
摘要
Abstract
Microgravity and ionizing radiation during long-term space flight are the main reasons for the decline of astronauts'cognitive function.As resident immune cells in the central nervous system of vertebrates,microglia are particularly important for the brain to maintain normal physiological function.However,there is no discussion about the role of microglia in cognitive impairment caused by long-term space flight.Therefore,this review first discus-ses the cognitive impairment caused by microgravity and ionizing radiation,and then discusses the possible role of microglia in long-term space flight from the role of microglia in cognitive dysfunction.and possible ways to treat or prevent cognitive impairment in the future.关键词
小胶质细胞/神经元/认知障碍/太空飞行Key words
microglia/neurons/cognitive impairment/spaceflight/分类
生物科学引用本文复制引用
孙精言,陈姿喧,邓玉林..小胶质细胞在太空飞行导致的认知障碍中的作用[J].生命科学仪器,2023,21(4):9-17,9.
