生命科学仪器2023，Vol.21Issue(4)：28-34,7.DOI:10.11967/2023210804
基于蒸汽的离体猪肝消融技术仿真及验证
Study on the key technologies of steam thermal ablation of tumors
摘要
Abstract
Currently,tumor hyperthermia has become one of the important methods for treating patients,and now the existing thermal ablation methods have certain shortcomings,leading to inevitable adverse reactions in patients after treatment.Therefore,finding a new green ablation method is a research hotspot nowadays.In order to solve the problems of carbonization of ablation centers and high difficulty in temperature control caused by commonly used thermal ablation methods,based on fluid motion and biological heat transfer theory,this paper designs a steam abla-tion simulation model using high-temperature water vapor as the medium,improves experimental instruments and equipment by analyzing the changes of temperature field calculated by the simulation,and formulates a test plan.U-sing new equipment and experimental ideas and making porcine livers as experimental materials,we realized the ex-perimental effect ofaxial ratio above 80％and ablation radius above 3 cm,which verified the feasibility of steam abla-tion in some ways.The steam ablation simulation model and steam ablation experiment designed in this paper pro-vide a new research direction and theoretical basis for the subsequent green ablation simulation and experiment.关键词
蒸汽/温度梯度/仿真/猪肝Key words
Steam/Temperature gradient/Simulation/Porcine liver分类
能源科技引用本文复制引用
宋毅,晋晓飞,钱志余..基于蒸汽的离体猪肝消融技术仿真及验证[J].生命科学仪器,2023,21(4):28-34,7.基金项目
国家自然科学基金重大科研仪器研制项目(81827803,81727804),国家自然科学基金指南引导类原创探索计划项目(82151311)国家自然科学基金(61875085,11902154),江苏省重点研发计划(社会发展)项目(BE2020705),江苏省自然科学基金(BK20190387). （81827803,81727804）
