超高效液相色谱-高分辨质谱法检验4种酰胺类合成大麻素同分异构体OACSTPCD
Determination of four amide synthetic cannabinoid isomers by ultra-high performance liquid chromatography-high resolution mass spectrometry
同分异构现象在合成大麻素中普遍存在,因其结构与性质上的差异并不显著,当同时存在时分离鉴定较为困难,为公安实践中合成大麻素的检验鉴定带来了一定的挑战.本研究利用超高效液相色谱-高分辨质谱技术(UH-PLC-HRMS)建立了 5F-EMB-PICA与 5F-MDMB-PICA、ADB-BINACA与AB-PINACA这 2 对酰胺类合成大麻素同分异构体的检验方法.选用Hypersil GOLD C18色谱柱(100 mm×2.1 mm,1.9 μm)…查看全部>>
Isomerization commonly occurs in synthetic cannabinoids(SCs).Owing to the few differences in their structure and properties,it is difficult to simultaneously separate and identi-fy them.Thus,the identification of synthetic cannabinoids is challenging,posing a threat to public security.This study aims to separate and identify four SCs,which are 2-[1-(5-fluoropen-tyl)-1H-indole-3-formylamino]-3,3-dimethylbutyrate methyl ester(5F-MDMB-PICA),2-[1-(5-fluoropentyl…查看全部>>
汤睿阳;王继芬;肖婷月;覃仕扬;接昭玮;张傲林
中国人民公安大学侦查学院,北京 100038中国人民公安大学侦查学院,北京 100038中国人民公安大学侦查学院,北京 100038北京市公安司法鉴定中心,法庭毒物分析公安部重点实验室,北京 100192中国人民公安大学侦查学院,北京 100038中国人民公安大学侦查学院,北京 100038
化学
超高效液相色谱-高分辨质谱合成大麻素同分异构体
ultra-high performance liquid chromatography-high resolution mass spectroscopy(UHPLC-HRMS)synthetic cannabinoids(SCs)isomers
《色谱》 2024 (1)
84-91,8
中国人民公安大学刑事科学技术双一流创新研究专项(2023SYL06). Double First-Class Innovation Research Project for People's Public Security University of China(No.2023SYL06).
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