生物医学工程研究2023，Vol.42Issue(4)：356-361,6.DOI:10.19529/j.cnki.1672-6278.2023.04.08
基于计算机断层扫描图像的房颤患者左心耳封堵前后的血流模拟
Blood flow simulation in patients with atrial fibrillation before and after left atrial appendage occlusion based on CT image
徐庆虎 1张天逸 1程云章1
作者信息
- 1. 上海理工大学 健康科学与工程学院,上海 200093||上海介入医疗器械工程技术研究中心,上海 200093
- 折叠
摘要
Abstract
To investigate the hemodynamic changes of patients before and after left atrial appendage occlusion,we established a computational fluid dynamics(CFD)model before and after occlusion of the left atrial appendage based on CT images and perform nu-merical simulation.Firstly,a three-dimensional model was reconstructed by using CT images of patients with atrial fibrillation.Then,hemodynamic numerical simulation was performed on the CFD model.Hemodynamic parameters such as blood flow velocity,time aver-age wall shear stress(TAWSS)and oscillation shear index(OSI)were obtained and compared before and after occlusion.Simulation results showed that the left atrial ear could improve the state of intra-atrial blood flow disorder,and improve the distribution of TAWSS and OSI on the atrial wall,which could effectively reduce the risk of thromboembolism in patients to a certain extent.It can provide some theoretical support for clinical medicine.关键词
左心耳封堵术/计算流体力学/血流动力学特征/房颤/CT图像Key words
Left atrial appendage occlusion/Computational fluid dynamics/Hemodynamic characteristics/Atrial fibrillation/CT image分类
医药卫生引用本文复制引用
徐庆虎,张天逸,程云章..基于计算机断层扫描图像的房颤患者左心耳封堵前后的血流模拟[J].生物医学工程研究,2023,42(4):356-361,6.
