世界中医药2023,Vol.18Issue(21):3149-3155,7.DOI:10.3969/j.issn.1673-7202.2023.21.026
微生物-脑-肠轴与脑卒中后抑郁的研究进展
Research Grogress of Microbiota-gut-brain Axis and Post-stroke Depression
摘要
Abstract
Post-stroke depression(PSD)refers to a series of emotional disorder syndromes characterized by depression and lack of interest except for the symptoms of stroke,and it is often accompanied by physical symptoms.Microbiota-gut-brain axis refers to the continuous two-way communication between the central nervous system and the gastrointestinal tract.The interaction in the microbi-ota-gut-brain axis may play a role in the pathogenesis of PSD.Therefore,combined with the research progress in China and abroad,this paper discussed the main role of microbiota-gut-brain axis in PSD,so as to provide new ideas for the treatment of PSD.关键词
微生物/脑卒中后抑郁/微生物-脑-肠轴/肠道菌群/益生菌/粪便移植Key words
Microbiota/PSD/Microbiota-gut-brain axis/Intestinal flora/Probiotics/Fecal transplantation分类
中医学引用本文复制引用
许慧,李恋秋,周鑫,刘辉,叶海敏..微生物-脑-肠轴与脑卒中后抑郁的研究进展[J].世界中医药,2023,18(21):3149-3155,7.基金项目
湖南省自然科学基金项目(2021JJ30519)——基于肠道微生物探讨电针"四关"穴对脑卒中后抑郁大鼠神经炎症的调控机制 (2021JJ30519)
湖南中医药大学校级科研基金项目(2020XJJJ056) (2020XJJJ056)