实验动物与比较医学2023，Vol.43Issue(6)：659-668,10.DOI:10.12300/j.issn.1674-5817.2023.142
《动物研究:体内实验报告》即ARRIVE 2.0指南的解释和阐述(四)
Explanation and Elaboration for the ARRIVE Guidelines 2.0—Reporting Animal Research and In Vivo Experiments(Ⅳ)
摘要
Abstract
Improving the reproducibility of biomedical research results is a major challenge.Transparent and accurate reporting of the research process enables readers to evaluate the reliability of the research results and further explore the experiment by repeating it or building upon its findings.The ARRIVE 2.0 guidelines,released in 2019 by the UK National Centre for the Replacement,Refinement and Reduction of Animals in Research(NC3Rs),provide a checklist applicable to any in vivo animal research report.These guidelines aim to improve the standardization of experimental design,implementation,and reporting,as well as the reliability,repeatability,and clinical translatability of animal experimental results.The use of ARRIVE 2.0 guidelines not only enriches the details of animal experimental research reports,ensuring that information on animal experimental results is fully evaluated and utilized,but also enables readers to understand the content expressed by the author accurately and clearly,promoting the transparency and integrity of the fundamental research review process.At present,the ARRIVE 2.0 guidelines have been widely adopted by international biomedical journals.This article is a Chinese translation based on the best practices of international journals following the ARRIVE 2.0 guidelines in international journals,specifically for the complete interpretation of the ARRIVE 2.0 guidelines published in the PLoS Biology journal in 2020(original text can be found at https://arriveguidelines.org).The fourth part of the article includes the items 1-5 of ARRIVE 2.0 Recommended 11 section,which covers"Abstract""Background""Objectives""Ethical statement"and"Housing and husbandry".Its aim is to promote the full understanding and use of the ARRIVE 2.0 guidelines by domestic researchers,enhance the standardization of experimental animal research and reporting,and promote the high-quality development of experimental animal technology and comparative medicine research in China.关键词
动物实验/ARRIVE 2.0指南/ARRIVE推荐11条/摘要/研究背景/研究目标/伦理声明/饲养场所和饲养Key words
Animal experiment/ARRIVE 2.0 guidelines/ARRIVE recommended 11/Abstract/Background/Objectives/Ethical statement/Housing and husbandry分类
医药卫生引用本文复制引用
李夏莹,陶雨风,庞万勇,韦玉生,田永路,刘晓宇,卢选成,陈国元,卢晓,白玉,高静,李垚..《动物研究:体内实验报告》即ARRIVE 2.0指南的解释和阐述(四)[J].实验动物与比较医学,2023,43(6):659-668,10.基金项目
国家重点研发计划"实验动物共性关键质量评价技术标准研究"(2022YFF0711000) （2022YFF0711000）
中国科学技术期刊编辑学会2023年翰笔计划医学中青年编辑科研项目"动物实验医学研究及报告规范化的国际对标(指南汉化推广)"(HBJH-2023-A16) （指南汉化推广）
