实用肝脏病杂志2024，Vol.27Issue(1)：92-95,4.DOI:10.3969/j.issn.1672-5069.2024.01.024
影响肝细胞癌患者肿瘤微血管侵犯的多因素分析
Risk factors for microvascular invasion in patients with hepatocellular carcinoma
摘要
Abstract
Objective The aim of this study was to investigate the risk factors for microvascular invasion(MVI)in patients with hepatocellular carcinoma(HCC).Methods 206 patients with HCC were encountered in our hospital between March 2018 and March 2022,and all underwent MRI and hepatectomy.The MVI was diagnosed by histopathology.The univariate and multivariate Logistic regression analysis were applied to predict the existence of MVI in patients with HCC.Results Out of the 206 patients with HCC,the MVI was found in 50 cases(24.3%);there were no significant differences as respect to serum AFP levels,Child-Pugh classes and the tumor envelope intact or not between patients with and without MVI(P>0.05),while the percentages of tumor diameter≥5 cm and low tumor cell differentiation in patients with MVI were56.0%and58.0%,both much higher than 32.7%and 35.3%(P<0.05)in patients without MVI;the multivariate Logistic regression analysis showed that the tumor diameter≥5 cm and low tumor cell differentiation were the independent risk factors for the existence of MVI in patients with HCC(OR=1.166,OR=1.141,bot P<0.05).Conclusion The large tumor and low differentiation of tumor cells are the independent risk factors of MVI happening in patients with HCC,and the preoperative imaging could help determine the size of tumors,and thus make the therapeutic strategy.关键词
肝细胞癌/磁共振成像/肝叶切除术/微血管侵犯/多因素Logistic回归分析Key words
Hepatoma/Magnetic resonance imaging/Hepatectomy/Microvascular invasion/Multivariate Logistic regression analysis引用本文复制引用
许梁,梁宏伟,杜圣,黄爱娜,张涛..影响肝细胞癌患者肿瘤微血管侵犯的多因素分析[J].实用肝脏病杂志,2024,27(1):92-95,4.基金项目
江苏省南通市卫生健康委员会科研课题(编号:MA2021026) （编号:MA2021026）
