实用肝脏病杂志2024，Vol.27Issue(1)：117-120,4.DOI:10.3969/j.issn.1672-5069.2024.01.030
微波消融与腹腔镜肝叶切除术治疗肝血管瘤患者疗效研究
Comparison of microwave ablation and laparoscopic hepatectomy in the treatment of patients with hepatic hemangiomas
摘要
Abstract
Objective The purpose of this study was to compare the efficacy of microwave ablation(MWA)and laparoscopic hepatectomy(LH)in the treatment of patients with hepatic hemangiomas(HH).Methods 94 patients with HH were admitted to our hospital between January 2018 and March 2022,and were divided into two groups,receiving MWA in 46 cases and LH in48 cases.All patients were followed-up for 1 year after operation.Serum tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)levels were determined by ELISA.Results The intraoperative blood loss,blood flow blocking time,operation time and hospital stay in MWA-treated patients were(17.2±3.5)mL,(22.8±4.4)min,(158.0±31.8)min and(6.3±1.9)d,all significantly less or shorter than[(208.4±39.7)mL,(26.3±5.1)min,(228.5±43.2)min and(8.1±2.4)d,respectively,P<0.05]in patients receiving LH treatment;there were no significant differences as respect to liver function tests between the two groups before and after operation(P>0.05);five days after operation,serum TNF-α and IL-6 levels in patients with MWA treatment were(51.3±7.5)pg/ml and(18.3±3.5)pg/ml,both significantly lower than[(65.9±10.4)pg/ml and(26.8±4.9)pg/ml,respectively,P<0.05]in LH-treated patients;the incidences of post-operational complications,such as infections and bile leakage,in MWA-and LH-treated patients were 4.4%and 8.3%(P>0.05);at the end of one-year follow-up,no intrahepatic tumors relapsed in LH-treated patients,and the tumors shrank to25%in43 cases(93.5%)in MWA-treated patients.Conclusion The patients with HH could be managed by both MWA or LH,but we recommend the former because of the less body inflammatory reactions and rapid recovery.关键词
肝血管瘤/微波消融/腹腔镜肝叶切除术/治疗Key words
Hepatic hemangiomas/Microwave ablation/Laparoscopy hepatectomy/Treatment引用本文复制引用
陶国清,许其威,李海锋..微波消融与腹腔镜肝叶切除术治疗肝血管瘤患者疗效研究[J].实用肝脏病杂志,2024,27(1):117-120,4.基金项目
山西省科技厅科技攻关计划项目(编号:20210313013-2) （编号:20210313013-2）
