天津中医药2024，Vol.41Issue(1)：117-122,6.DOI:10.11656/j.issn.1672-1519.2024.01.22
基于线粒体功能探讨培宗气理论治疗慢性阻塞性肺疾病的机制研究
Based on the function of mitochondria to explore the internal mechanism of zongqi theory in treating of chronic obstructive pulmonary disease
摘要
Abstract
Chronic obstructive pulmonary disease(COPD)is a common and frequently occurring disease of the respiratory system.Due to its high disability rate,it has a serious negative impact on the quality of life and socio-economic development of patients.Traditional Chinese medicine believes that"deficiency,phlegm,and blood stasis"are its core pathogenesis,and the rise and fall of zongqi runs through the entire evolution of its pathogenesis.The method of peitu shengjin is a representative treatment method for COPD based on the theory of zongqi,which has been widely used in clinical treatment of COPD.Modern medicine has confirmed that mitochondrial functional and morphological disorders are important biological mechanisms for the occurrence and development of COPD pathology and pathophysiology.This article starts from the internal relationship between"deficiency,phlegm,blood stasis"and mitochondrial function,and explores the role and mechanism of zongqi theory and the method of cultivating soil and generating gold in the treatment of COPD,in order to provide basis and guidance for its clinical application.关键词
慢性阻塞性肺疾病/宗气理论/培土生金/线粒体Key words
chronic obstructive pulmonary disease/zongqi theory/peitu shengjin/mitochondria分类
医药卫生引用本文复制引用
吴清原,郭思佳,孙增涛,李晓丹..基于线粒体功能探讨培宗气理论治疗慢性阻塞性肺疾病的机制研究[J].天津中医药,2024,41(1):117-122,6.基金项目
国家自然科学基金项目(81874398,81874444,8210152432) （81874398,81874444,8210152432）
"十二五"特色学科"中医内科学"(20200402) （20200402）
天津市高等学校"创新团队培养计划"项目(TD13-5051). （TD13-5051）
