天津中医药2024，Vol.41Issue(1)：123-129,7.DOI:10.11656/j.issn.1672-1519.2024.01.23
姜黄素及其与化疗药物的纳米递药系统协同抗肿瘤作用研究
Synergistic anti-tumor effects of curcumin and its nanodrug delivery system with chemotherapeutic drugs
摘要
Abstract
As the incidence of cancer is increasing year by year,the use of a single chemotherapeutic drug in the treatment of cancer is prone to multidrug resistance.Therefore,and drug combinations therapy can play a greater advantage in clinical treatment.Curcumin is a lipophilic polyphenolic extracted from Curcuma longa L.,a traditional Chinese medicine(TCM)for promoting blood circulation and removing blood stasis.It has wide range of pharmacological activities.It can be used in combination with chemotherapeutic drugs to exert synergistic anti-cancer effects and overcome multidrug resistance,which has become a research hotspot in the medical field.Based on the anti-cancer effects of curcumin and nanodrug delivery systems,this work focuses on the synergistic nanodrug delivery system of curcumin combined with chemotherapeutic drugs,so as to provide a reference for the efficient delivery of anti-tumour drugs.关键词
姜黄素/多药耐药/纳米递药系统/抗肿瘤Key words
curcumin/multidrug resistance/nano-delivery systems/anti-tumour分类
医药卫生引用本文复制引用
王薪淇,方玉秋,尚瑞鹏,汪子贵,齐学洁,纪岩..姜黄素及其与化疗药物的纳米递药系统协同抗肿瘤作用研究[J].天津中医药,2024,41(1):123-129,7.基金项目
天津市教委重点项目(2022ZD041). （2022ZD041）
