颈动脉支架植入术联合规范脑血管病二级预防对颈内动脉颅外段重度狭窄患者的效果观察OA
To Observe the Effect of Carotid Artery Stenting Combined with Standardized Secondary Prevention of Cerebrovascular Disease on Patients with Severe Extracranial Internal Carotid Artery Stenosis
目的 探究颈动脉支架植入术联合规范脑血管病二级预防对颈内动脉颅外段重度狭窄患者认知功能影响的效果.方法 选取 2021 年 9 月至 2023 年 3 月期间在济南市第三人民医院收治的 68 例颈内动脉颅外段重度狭窄患者,根据治疗方式不同将其分为对照组和观察组各 34 例.基础疾病治疗基础上,对照组采取规范的脑血管病二级预防,观察组完成颈动脉支架植入术,并坚持规范的脑血管病二级预防,比较两组精神状态、认知功能、不良情绪、日常生活活动能力及神经功能缺损评分情况.结果 治疗后,两组患者的简易精神状态量表(MMSE)、蒙特利尔认知评估量表(MoCA)评分均有所提高,且观察组高于对照组,差异有统计学意义(P＜0.05).治疗后,两组患者的汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评分均有所下降,且观察组低于对照组,差异有统计学意义(P＜0.05).治疗后,两组患者的日常生活能力评定量表(ADL)评分均有所提高,且观察组高于对照组,差异有统计学意义(P＜0.05).治疗后,两组患者的神经功能缺损(NIHSS)评分均有所降低,观察组低于对照组,差异有统计学意义(P＜0.05).结论 颈动脉支架植入术联合规范脑血管病二级预防能够显著改善颈内动脉颅外段重度狭窄患者的精神状态、认知功能、不良情绪、日常生活活动能力和神经功能缺损.这一治疗策略有助于提升患者的生活质量和康复效果.
Objective To investigate the effect of carotid artery stenting combined with standard secondary prevention of cerebrovascular disease on cognitive function in patients with severe extracranial stenosis of the internal carotid artery.Methods A total of 68 patients with severe extracranial stenosis of the internal carotid artery treated in the Third People's Hospital of Jinan from September 2021 to March 2023 were selected and divided into control group and observation group with 34 patients in each group according to different treatment methods.On the basis of basic disease treatment,the control group adopted standard secondary prevention of cerebrovascular disease,while the observation group completed carotid artery stent implantation and adhered to standard secondary prevention of cerebrovascular disease.The mental state,cognitive function,adverse mood,activity of daily living,and neurological function deficit score were compared between the two groups.Results After treatment,the scores of mini-mental state examination(MMSE)and montreal cognitive assessment(MoCA)in the two groups were improved,and the scores in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).After treatment,the scores of the Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)in both groups decreased,and the observation group was lower than the control group,the difference was statistically significant(P＜0.05).After treatment,the activity of daily living scale(ADL)scores of both groups were improved,and the observation group was higher than the control group,the difference was statistically significant(P＜0.05).After treatment,the neurological impairment(NIHSS)score of both groups was decreased,and the observation group was lower than the control group,the difference was statistically significant(P＜0.05).Conclusion Carotid artery stenting combined with standard secondary prevention of cerebrovascular disease can significantly improve the mental state,cognitive function,adverse mood,activities of daily living,and neurological deficits in patients with severe extracranial stenosis of the internal carotid artery.This treatment strategy helps improve the quality of life and recovery effect of patients.
李秉龙;韩丰月;刘琳;郭鹏
济南市第三人民医院 神经内科,山东 济南 250000
临床医学
颈动脉支架植入术规范脑血管病二级预防颈内动脉颅外段重度狭窄认知功能
carotid artery stentingstandardize the secondary prevention of cerebrovascular diseasessevere extracranial stenosis of the internal carotid arterycognitive function
《临床研究》 2024 (001)
4-7 / 4
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