血常规相关指标及心肌酶谱对脑梗死患者预后的评估意义OA
The Significance of Blood Routine Related Indexes and Myocardial Enzyme Spectrum in Evaluating the Prognosis of Patients with Cerebral Infarction
目的 探究血常规相关指标及心肌酶谱对脑梗死患者预后的评估意义.方法 选取 2019 年 3 月至 2022 年 3月徐汇区大华医院收治的 84 例脑梗死患者为研究对象,并依据预后情况分为预后不良组和预后良好组.比较两组患者的临床资料,检测患者的白细胞计数(WBC)、中心粒细胞(Neu)水平及天门冬氨酸氨基转移酶(AST)水平.Logistic多因素回归分析影响脑梗死患者预后的有关因素.分析AST、WBC、Neu对脑梗死患者预后不良的预测价值.结果 本研究 84 例脑梗死患者出院后 1 个月共有 15 例预后不良,预后不良发生率为 17.86%.比较两组患者AST、WBC、Neu水平,差异有统计学意义(P<0.05),预后不良组均高于预后良好组.两组一般资料、高血脂、血红蛋白比较,差异无统计学意义(P>0.05).Logistic多因素回归分析显示,WBC、Neu、AST均为影响脑梗死患者预后不良的危险因素,差异有统计学意义(OR=2.857,3.010,3.374,P<0.05),血常规相关指标及心肌酶谱对脑梗死患者预后不良进行预测,联合的AUC为 0.952,高于血常规相关指标及心肌酶谱水平单独进行评估的特异度,差异有统计学意义(P<0.05).结论 血常规相关指标及心肌酶谱在脑梗死患者预后的预测效能较高,值得临床应用.
Objective To explore the significance of blood routine index and myocardial enzyme spectrum in evaluating the prognosis of patients with cerebral infarction.Methods A total of 84 patients with cerebral infarction admitted to Dahua Hospital of Xuhui District from March 2019 to March 2022 were selected as the research objects and were divided into a poor prognosis group and a good prognosis group according to the prognosis.The clinical data of the two groups were compared,and the white blood cell count(WBC),neutrophil(Neu)level,and aspartate aminotransferase(AST)level were detected.Logistic multivariate regression analysis of prognostic factors in patients with cerebral infarction.To analyze the prognostic value of AST,WBC,and Neu in patients with cerebral infarction.Results In this study,15 of 84 patients with cerebral infarction had poor prognosis one month after discharge,and the incidence of poor prognosis was 17.86%.The levels of AST,WBC,and Neu were compared between the two groups,and the differences were statistically significant(P<0.05).The poor prognosis group was higher than the good prognosis group.There was no significant difference in general information,hyperlipidemia,and hemoglobin between the two groups(P>0.05).Logistic multivariate regression analysis showed that WBC,Neu,and AST were all risk factors for poor prognosis in patients with cerebral infarction,and the difference was statistically significant(OR=2.857,3.010,3.374,P<0.05).Routine blood-related index and myocardial enzyme spectrum to predict the prognosis in patients with cerebral infarction,the combined AUC is 0.952,higher than that of the routine blood-related index and myocardial enzyme levels alone to evaluate specific degrees,the difference was statistically significant(P<0.05).Conclusion The correlation indexes of blood routine and myocardial enzyme spectra are effective in predicting the prognosis of patients with cerebral infarction and are worthy of clinical application.
杨明娜;浦苏颖
上海市徐汇区大华医院 神经内科,上海 200237
基础医学
白细胞计数中心粒细胞心肌酶谱脑梗死患者
white blood cell countneutrophilsmyocardial enzyme spectrumpatients with cerebral infarction
《临床研究》 2024 (001)
12-15 / 4
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