眼科新进展2024,Vol.44Issue(1):62-65,4.DOI:10.13389/j.cnki.rao.2024.0012
自主神经对房水流出通道的调控作用
Regulatory effect of autonomic nerve on aqueous humor outflow pathway
摘要
Abstract
Glaucoma is the leading irreversible blinding eye disease worldwide,and intraocular pressure(IOP)plays a key role in the occurrence and development of glaucoma.However,the underlying IOP regulatory mechanism remains un-clear.Currently,clinical IOP-lowering drugs work either by reducing aqueous humor formation or increasing aqueous hu-mor outflow with limited reduction amplitude.Recent studies demonstrate that IOP may be regulated by autonomic nerves.To understand the distribution and regulatory mechanism of autonomic nerves in the aqueous humor outflow pathway and provide new ideas for IOP-lowering study and novel drug exploration,we review the roles of the autonomic nervous system in the formation and outflow of aqueous humor in this article.关键词
自主神经/青光眼/房水流出通道/眼压Key words
autonomic nerve/glaucoma/aqueous humor outflow pathway/intraocular pressure分类
临床医学引用本文复制引用
韩佳伶,徐丽娟,江晓睿,周涛,梁远波..自主神经对房水流出通道的调控作用[J].眼科新进展,2024,44(1):62-65,4.基金项目
国家自然科学基金(编号:82201177) (编号:82201177)
国家重点研发计划(编号:2020YFC2008200) (编号:2020YFC2008200)
浙江省"尖兵""领雁"研发攻关计划(编号:2022C03112) (编号:2022C03112)
浙江省万人计划科技创新领军人才(编号:2021R52012) (编号:2021R52012)
浙江省医药卫生项目(编号:2023KY914) (编号:2023KY914)
浙江省高校领军人才培养计划(编号:2020099) (编号:2020099)