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中枢神经系统表面铁沉积症的临床分析

周若琳 孙莉 王梓铖 齐一鸣 张海宁

中风与神经疾病杂志2023,Vol.40Issue(12):1089-1095,7.
中风与神经疾病杂志2023,Vol.40Issue(12):1089-1095,7.DOI:10.19845/j.cnki.zfysjjbzz.2023.0235

中枢神经系统表面铁沉积症的临床分析

Superficial siderosis of the central nervous system:A literature analysis and case report

周若琳 1孙莉 1王梓铖 1齐一鸣 1张海宁1

作者信息

  • 1. 吉林大学白求恩第一医院神经内科认知障碍疾病诊疗中心,吉林 长春 130021
  • 折叠

摘要

Abstract

Objective To investigate the etiology,clinical manifestations,imaging features,and treatment of su-perficial siderosis of the central nervous system(SSCNS).Methods A patient confirmed with SSCNS was reported.Sixty-one patients confirmed with SSCNS were found through a search of China National Knowledge Infrastructure and Wanfang Data and were analyzed in categories for the epidemiology,etiology,clinical manifestations,and laboratory test results.Results Among the 61 patients with SSCNS reported in the literature,ataxia was the most common clinical symptom(49 cases,80%),followed by hearing loss(43 cases,70%)and pyramidal signs(30 cases,49%).A probable cause was found in 25(39%)of these cases.Conclusion SSCNS can last for several years or even decades,with hearing loss,ataxia,and pyramidal signs as its main clinical symptoms.Magnetic resonance imaging is the most valuable basis for diag-nosis,and susceptibility-weighted imaging is more sensitive in the diagnosis of microhemorrhage.

关键词

中枢神经系统/含铁血黄素沉积/共济失调

Key words

Central nervous system/Hemosiderin deposition/Ataxia

分类

医药卫生

引用本文复制引用

周若琳,孙莉,王梓铖,齐一鸣,张海宁..中枢神经系统表面铁沉积症的临床分析[J].中风与神经疾病杂志,2023,40(12):1089-1095,7.

基金项目

吉林省医疗卫生人才专项(JLSWSRCZX2021-077) (JLSWSRCZX2021-077)

中风与神经疾病杂志

OACSTPCD

1003-2754

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