中国药业2024，Vol.33Issue(1)：122-124,3.DOI:10.3969/j.issn.1006-4931.2024.01.027
1例口服雄黄制剂致白血病患儿急性砷中毒死亡原因分析
Lethal Cause of Acute Arsenic Poisoning Caused by Oral Realgar Preparations in the Treatment of a Child with Leukemia:A Case Report
摘要
Abstract
Objective To investigate the cause of acute arsenic poisoning caused by realgar preparations.Methods A retrospective analysis was conducted on the diagnosis and treatment of acute arsenic poisoning caused by oral realgar preparations in a child with leukemia.The characteristics of arsenic poisoning in the child with leukemia treated with realgar preparations and the treatment precautions were summarized.Results The daily dosage of realgar in the child was 1 g,which was much higher than the daily dosage of a single ingredient of 50-100 mg.The clinical symptom was multiple organ failure,with a urine arsenic content of 33.56 μmol/L,far exceeding the normal value of human urine arsenic(1.8 μmol/L),and the child was diagnosed as acute arsenic poisoning.Conclusion The daily dosage of realgar for the child belongs to overdose medication.The dosage and course of treatment of realgar preparations should meet the requirements of the drug package insert,and should not be taken for a long time or overdose.Once arsenic poisoning symptoms such as arrhythmia and prolonged QT interval on electrocardiogram occur,the medication should be stopped immediately to ensure the medication safety of the patient.关键词
雄黄/儿童白血病/急性砷中毒/致死原因Key words
realgar/childhood leukemia/acute arsenic poisoning/lethal cause分类
医药卫生引用本文复制引用
彭军,张丽荣,杨光,凌云..1例口服雄黄制剂致白血病患儿急性砷中毒死亡原因分析[J].中国药业,2024,33(1):122-124,3.
