中国现代医学杂志2023，Vol.33Issue(24)：12-16,5.DOI:10.3969/j.issn.1005-8982.2023.24.003
双期增强CT扫描联合血浆Presepsin水平对急性肾盂肾炎的诊断价值
Diagnostic value of two-phase contrast-enhanced CT combined with the plasma level of presepsin for acute pyelonephritis
摘要
Abstract
Objective To investigate the diagnostic value of two-phase contrast-enhanced CT combined with the plasma level of soluble cluster of differentiation 14 subtype(presepsin)for acute pyelonephritis(APN).Methods The clinical data of 95 patients with urinary tract infection admitted to The First People's Hospital of Fuzhou from March 2019 to May 2020 were retrospectively analyzed.According to the clinical diagnosis,the patients were divided into the non-APN group(n=42)and the APN group(n=53),and those with APN were subdivided into the non-critical group(n=34)and the critical group(n=19)according to the severity of the disease.The general data and the plasma level of presepsin were compared between the APN group and the non-APN group,and the plasma level of presepsin was also compared between the critical group and the non-critical group.The consistency between the findings of the two-phase contrast-enhanced CT and the clinical diagnosis was analyzed,and the diagnosis made via the findings of the two-phase contrast-enhanced CT combined with the plasma level of presepsin was compared with the clinical diagnosis as well.The receiver operating characteristic(ROC)curve was plotted to analyze the diagnostic value of two-phase contrast-enhanced CT combined with the plasma level of presepsin for APN.Results There was no difference in sex composition,age,duration of urinary tract infection and body mass index between the APN group and the non-APN group(P＞0.05).The plasma level of presepsin in the APN group was higher than that in the non-APN group(P＜0.05),and the plasma level of presepsin in the critical group was higher compared with that in the non-critical group(P＜0.05).The consistency between findings of the two-phase contrast-enhanced CT and the clinical diagnosis was fair(Kappa=0.725,P=0.012),while the consistency between the diagnosis made via the findings of the two-phase contrast-enhanced CT combined with the plasma level of presepsin and the clinical diagnosis was good(Kappa=0.798,P=0.005).ROC curve analysis revealed that the sensitivities of two-phase contrast-enhanced CT,the plasma level of presepsin,and their combination for diagnosing APN were 88.68％(95％CI:0.767,0.923),79.25％(95％CI:0.673,0.865)and 93.34％(95％CI:0.634,0.978),with the specificities being 73.81％(95％CI:0.528,0.835),71.43％(95％CI:0.501,0.827),and 90.48％(95％CI:0.696,0.982),and the areas under the ROC curves being 0.812(95％CI:0.719,0.885),0.717(95％CI:0.615,0.804),and 0.924(95％CI:0.851,0.968),respectively.Conclusions Two-phase contrast-enhanced CT and the plasma level of presepsin can be used to diagnose APN,and the combination of the two exhibits a higher diagnostic value.关键词
急性肾盂肾炎/双期增强CT扫描/Presepsin/诊断价值Key words
acute pyelonephritis/two-phase contrast-enhanced CT scan/soluble cluster of differentiation 14 subtype/diagnostic value分类
医药卫生引用本文复制引用
邹琪,黎志鹏,鲁广亮..双期增强CT扫描联合血浆Presepsin水平对急性肾盂肾炎的诊断价值[J].中国现代医学杂志,2023,33(24):12-16,5.基金项目
江西省自然科学基金(No:20212BAB206062) （No:20212BAB206062）
江西省卫生健康委科研课题(No:20194090) （No:20194090）
