中国实验动物学报2023，Vol.31Issue(11)：1485-1497,13.DOI:10.3969/j.issn.1005-4847.2023.011.013
活体脑部神经递质检测技术的研究进展
Research progress of neurotransmitter detection technology in live brains
摘要
Abstract
As endogenous chemical substances,neurotransmitters play a vital role in maintaining normal life activities.Abnormal levels of neurotransmitters can lead to physical,mental,and some neurodegenerative diseases.However,the ultralow concentration,complex chemical properties,and release modes of neurotransmitters make their accurate detection in vivo a great challenge.To accurately monitor neurotransmitters in the brain and accurately understand the release kinetics of neurotransmitters,we reviewed several method commonly used in the past five years to detect neurotransmitters in vivo and their research progress.The basic principle and applicability of microdialysis,electrochemical sensors,and fluorescence sensors are introduced in detail.关键词
神经递质/疾病/检测/活体Key words
neurotransmitter/disease/detection/live body分类
生物科学引用本文复制引用
朱铭钰,崔利利,陈欢,侯宏卫,胡清源..活体脑部神经递质检测技术的研究进展[J].中国实验动物学报,2023,31(11):1485-1497,13.基金项目
中国烟草总公司科技重大专项(110202101018(XX-04)),中国烟草总公司重点研发项目(110202102014).Funded by China National Tobacco Corporation Science and Technology Major Project(110202101018(XX-04)),China National Tobacco Corporation Key Research and Development Project(110202102014). （110202101018(XX-04）
