中国现代医学杂志2023，Vol.33Issue(24)：48-54,7.DOI:10.3969/j.issn.1005-8982.2023.24.009
Th17/Treg细胞免疫平衡的相关调控机制研究进展
Research advances in the regulatory mechanism of immune balance between Th17 and Treg cells
摘要
Abstract
The immune system recognizes and fights off pathogenic microorganisms and clears abnormally dividing cells in the body,and its balance is critical to maintaining normal responses and activities of the body.A variety of cells in the human body participate in the maintenance of immune homeostasis,among which T helper 17(Th 17)cells and regulatory T(Treg)cells play an essential role.The unbalanced immune system could lead to the occurrence of multiple immune diseases.The Th17/Treg cell balance is regulated in various ways involving cytokines,metabolism,intestinal microbiome,and post-translational modification.This review may provide novel insights and strategies for the treatment of immune diseases by summarizing the relevant mechanisms.关键词
辅助性T淋巴细胞17/调节性T淋巴细胞/翻译后修饰/肠道微生态Key words
T helper 17 cells/regulatory T cells/post-translational modification/intestinal microecology分类
医药卫生引用本文复制引用
徐炜,舒俊华,干意,涂丹娜..Th17/Treg细胞免疫平衡的相关调控机制研究进展[J].中国现代医学杂志,2023,33(24):48-54,7.基金项目
湖北省自然科学基金(No:2021CFB558) （No:2021CFB558）
湖北陈孝平科技发展基金会(No:CXPJJH121002-202117) （No:CXPJJH121002-202117）
