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斑马鱼肾损伤造模方法及评价指标的研究进展

兰爱琳 黄春华 夏铭 李茂娟 汪思齐 楼迪栋

中国比较医学杂志2023,Vol.33Issue(12):123-126,4.
中国比较医学杂志2023,Vol.33Issue(12):123-126,4.DOI:10.3969/j.issn.1671-7856.2023.12.019

斑马鱼肾损伤造模方法及评价指标的研究进展

Research progress on modeling methods and evaluation indexes of kidney injury in zebrafish

兰爱琳 1黄春华 1夏铭 1李茂娟 1汪思齐 1楼迪栋1

作者信息

  • 1. 贵州省法医中药毒理学特色重点实验室,贵州中医药大学司法鉴定所,贵阳 550000
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摘要

Abstract

Kidneys filter bloodand regulate fluid and electrolyte balances.However,the kidney is susceptible to toxicity of various compounds,Resulting in renal damage.Hence,prevention and treatment of renal injury is a hot research topic.Zebrafish is an ideal animal model,because it is closely related to humans in terms of morphology,physiology,and kidney functions and its response to compounds.In this article,we review the method and evaluation indexes of zebrafish kidney injury modeling.

关键词

斑马鱼/肾损伤/动物模型

Key words

zebrafish/kidney injury/animal models

分类

医药卫生

引用本文复制引用

兰爱琳,黄春华,夏铭,李茂娟,汪思齐,楼迪栋..斑马鱼肾损伤造模方法及评价指标的研究进展[J].中国比较医学杂志,2023,33(12):123-126,4.

基金项目

贵州省法医中药毒理学特色重点实验室(黔教合KY字[2021]004). (黔教合KY字[2021]004)

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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