中国医药科学2023,Vol.13Issue(23):126-129,4.DOI:10.20116/j.issn2095-0616.2023.23.29
特布他林与硫酸镁用于产时宫内复苏的临床研究
Clinical study of terbutaline and magnesium sulfate in intrauterine fetal resuscitation during labor
摘要
Abstract
Objective To explore the effect and safety of terbutaline in intrauterine fetal resuscitation(IUFR)during labor.Methods A total of 100 pregnant women with category Ⅱ fetal heart monitoring in Jiangxi Maternal and Child Health Hospital from June 2022 to June 2023 were selected and randomly divided into the terbutaline group and the magnesium sulfate group,with 50 cases in each group.The terbutaline group was given terbutaline sulfate 0.25 mg subcutaneously,while the magnesium sulfate group was given 25%magnesium sulfate 16 ml with 10%glucose solution 20 ml intravenously for 15-20 minutes.The success rate of IUFR,drug onset time,delivery mode,neonatal asphyxia,postpartum hemorrhage and adverse reactions of pregnant women were compared between the two groups,and the data were statistically analyzed.Results There was no significant difference in success rate of IUFR between the terbutaline group and the magnesium sulfate group(P>0.05).The drug onset time of the terbutaline group was significantly shorter than that of the magnesium sulfate group,with statistically significant difference(P<0.05).The neonatal asphyxia rate in the terbutaline group was lower than that in the magnesium sulfate group,with statistically significant difference(P<0.05).There was no significant difference in the rate of vaginal delivery and cesarean section due to fetal distress between the two groups(P>0.05).There was no significant difference in postpartum hemorrhage rate between the two groups(P>0.05).The incidence of adverse reactions requiring medical intervention in the terbutaline group was lower than that in the magnesium sulfate group,with statistically significant difference(P<0.05).Conclusion Terbutaline takes effect quickly and has few side effects when used in IUFR during labor.Therefore,it can be an option for emergency IUFR during labor.关键词
特布他林/硫酸镁/产时宫内复苏/胎儿窘迫Key words
Terbutaline/Magnesium sulfate/Intrauterine fetal resuscitation during labor/Fetal distress分类
医药卫生引用本文复制引用
邓秀英,彭秀秀..特布他林与硫酸镁用于产时宫内复苏的临床研究[J].中国医药科学,2023,13(23):126-129,4.基金项目
江西省卫生健康委科技计划(202211069). (202211069)