中国医学创新2023，Vol.20Issue(36)：144-150,7.DOI:10.3969/j.issn.1674-4985.2023.36.033
多种油脂肪乳在极低出生体重早产儿中的应用效果
Application Effect of Multi-oil Fat Emulsion in Very Low Birth Weight Premature Infants
摘要
Abstract
Objective:To analyze the clinical effect of Multi-oil Fat Emulsion(MOFE)in the treatment of very low birth weight(VLBW)premature infants.Method:A total of 45 VLBW premature infants treated in the First Affiliated Hospital of Gannan Medical University from January 2021 to November 2022 were selected as the observation objects.According to the random number table method,they were divided into the MOFE group,the Medium and Long Chain Fat Emulsion(MCFE/LCFE)group,and the Long Chain Fat Emulsion(LCFE)group,with 15 cases in each group.The treatment time,total hospitalization cost,incidence of complications,biochemical and inflammatory indicators and physical growth of the three groups were analyzed.Result:The duration of parenteral nutrition and length of hospital stay in the MOFE group were shorter than those in the MCFE/LCFE group and LCFE group,the total hospitalization cost of the MOFE group was less than that in the MCFE/LCFE group and LCFE group,the differences were statistically significant(P<0.05).The incidence of PNAC in the MOFE group was significantly lower than that in the MCFE/LCFE group and LCFE group,and the total incidence of complications in the MOFE group was lower than that in the MCFE/LCFE group and LCFE group,with statistical significance(P<0.05).The interaction effect of group and time about ALT,DBIL,TBA,GGT,TG,PCT,CRP,SAA,weight,head circumference and body length in the three groups were statistically significant(P<0.05),and the individual effects of time at different time points in the three groups were statistically significant(P<0.05).1-4 weeks after admission,the TG,CRP and SAA in the MOFE group was the lowest among the three groups;2-4 weeks after admission,the DBIL,TBA,PCT in the MOFE group were the lowest among the three groups;3-4 weeks after admission,the GGT in the MOFE group was the lowest among the three groups;4 weeks after admission,the body weight in the MOFE group was the highest among the three groups,the differences were statistically significant(P<0.05).Conclusion:Compared with MCFE/LCFE and LCFE,the use of MOFE in the nutritional treatment of VLBW premature infants can shorten the length of hospital stay,reduce the cost of treatment and reduce the occurrence of PNAC,and has advantages in regulating inflammatory response and has good safety.关键词
多种油脂肪乳/早产儿/极低出生体重Key words
Multi-oil Fat Emulsion/Premature infant/Very low birth weight引用本文复制引用
杨欣,陈北洋,湛健萍..多种油脂肪乳在极低出生体重早产儿中的应用效果[J].中国医学创新,2023,20(36):144-150,7.基金项目
赣州市卫生健康委员会市级科研计划项目(2022-2-079) （2022-2-079）
