浙江医学2023，Vol.45Issue(23)：2545-2548,2556,5.DOI:10.12056/j.issn.1006-2785.2023.45.23.2023-868
米库氯铵与顺式阿曲库铵在儿童腺样体手术肌松恢复效率比较
Comparison of muscle relaxation recovery efficacy between micuronium and cis-atracurium in pediatric adenoid surgery
摘要
Abstract
Objective To compare efficacy of muscle relaxation recovery between micuronium and cis-atracurium in pediatric adenoid surgery.Methods A total of 84 children with adenoid hypertrophy undergoing adenidectomy in Hangzhou Children's Hospital from August 2021 to May 2022 were randomly divided into micuronium(n=38)and cis-atracurium(n=46)groups;and the micuronium(0.2 mg/kg)or cis-acraconium(0.1 mg/kg)were used as muscle relaxants under the same induction and maintenance of anesthesia conditions in two groups.The heart rate(HR),oxygen saturation(SpO2),mean arterial pressure(MAP)and partial pressure of end-tidal carbon dioxide(PETCO2)before the induction of anesthesia(T0),beginning of operation(T1),end of operation(T2),extubation(T3)and 30 min after the extubation(T4)were compared between two groups.The time from the end of the operation to the TOF reaching 0.9,recovery index(RI),time to extubation,stay time in PACU after anesthesia,TOF value and myopasone residual rate at extubation,adverse reactionswere were also compared.Results There were no significant differences in HR,SpO2,MAP and PETCO2 at time points T0-T4 between two groups(all P＞0.05).The time from the end of the operation to the TOF reaching 0.9,RI,time to extubation,and PACU time in micuronium group were significantly lower than those in cis-acracurium group(all P＜0.05).The TOF in micuronium group was significantly higher than that in cis-atracurium group(P＜0.05).The myopasone residual rate in micuronium group was significantly lower than that in cis-atracurium group(P＜0.05).Conclusion Both micuronium and cis-atracurium meet the clinical needs,while the residual neuromuscle block of micuronium is less likely to occur.关键词
米库氯铵/顺式阿曲库铵/腺样体手术/肌松Key words
Micuronium/Cis-atracurium/Adenoid surgery/Muscle relaxation引用本文复制引用
叶国妹,陈依君,汪洁..米库氯铵与顺式阿曲库铵在儿童腺样体手术肌松恢复效率比较[J].浙江医学,2023,45(23):2545-2548,2556,5.
