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乳腺癌休眠机制研究进展

马澜婧 张百红

肿瘤防治研究2023,Vol.50Issue(12):1237-1242,6.
肿瘤防治研究2023,Vol.50Issue(12):1237-1242,6.DOI:10.3971/j.issn.1000-8578.2023.23.0602

乳腺癌休眠机制研究进展

Recent Insights into Mechanisms Governing Breast Cancer Dormancy

马澜婧 1张百红1

作者信息

  • 1. 730050 兰州,中国人民解放军联勤保障部队第940医院肿瘤科
  • 折叠

摘要

Abstract

Tumor dormancy refers to the status of disseminated cancer cells that remain in a viable yet not proliferating state for a prolonged period.Dormant cells will eventually"re-awake"resume their proliferation,and produce overt metastasis.The dormancy mechanism of cancer has attracted attention because of the close relationship between late recurrence and tumor dormancy.In this review,we illustrate the latest discoveries on the biological underpinnings of breast cancer dormancy and offer clinicians an overview of dormancy in breast cancer to guide them in the basic understanding of the complexity that underlies this process.

关键词

乳腺癌/肿瘤休眠/自噬/免疫逃逸/表观遗传/代谢重编程/肿瘤微环境/非编码RNA

Key words

Breast cancer/Tumor dormancy/Autophagy/Immune escape/Epigenetic/Metabolism reprogramming/Tumor microenvironment/Non-coding RNA

分类

医药卫生

引用本文复制引用

马澜婧,张百红..乳腺癌休眠机制研究进展[J].肿瘤防治研究,2023,50(12):1237-1242,6.

基金项目

Project of Gansu Provincial Youth Science and Technology Plan(No.22JR5RA021)甘肃省青年科技基金计划(22JR5RA021) (No.22JR5RA021)

肿瘤防治研究

OACSTPCD

1000-8578

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