肿瘤防治研究2023,Vol.50Issue(12):1237-1242,6.DOI:10.3971/j.issn.1000-8578.2023.23.0602
乳腺癌休眠机制研究进展
Recent Insights into Mechanisms Governing Breast Cancer Dormancy
摘要
Abstract
Tumor dormancy refers to the status of disseminated cancer cells that remain in a viable yet not proliferating state for a prolonged period.Dormant cells will eventually"re-awake"resume their proliferation,and produce overt metastasis.The dormancy mechanism of cancer has attracted attention because of the close relationship between late recurrence and tumor dormancy.In this review,we illustrate the latest discoveries on the biological underpinnings of breast cancer dormancy and offer clinicians an overview of dormancy in breast cancer to guide them in the basic understanding of the complexity that underlies this process.关键词
乳腺癌/肿瘤休眠/自噬/免疫逃逸/表观遗传/代谢重编程/肿瘤微环境/非编码RNAKey words
Breast cancer/Tumor dormancy/Autophagy/Immune escape/Epigenetic/Metabolism reprogramming/Tumor microenvironment/Non-coding RNA分类
医药卫生引用本文复制引用
马澜婧,张百红..乳腺癌休眠机制研究进展[J].肿瘤防治研究,2023,50(12):1237-1242,6.基金项目
Project of Gansu Provincial Youth Science and Technology Plan(No.22JR5RA021)甘肃省青年科技基金计划(22JR5RA021) (No.22JR5RA021)