中国中医药信息杂志2024,Vol.31Issue(1):6-10,5.DOI:10.19879/j.cnki.1005-5304.202301058
基于线粒体能量代谢探讨"阴中求阳"法治疗慢性心力衰竭科学内涵
Discussion on the Scientific Connotation of"Reinforcing Yang from Yin"Method in the Treatment of Chronic Heart Failure Based on Mitochondrial Energy Metabolism
摘要
Abstract
Chronic heart failure is the final stage of various cardiovascular diseases,and mitochondrial energy metabolism disorders have been proved to play an important role in the development of chronic heart failure.TCM believes that heart yin is the material basis of heart yang(qi),and deficiency of heart yang(qi)is the core pathogenesis of chronic heart failure.Based on mitochondrial energy metabolism,this article expounded the scientific connotation of"reinforcing yang from yin"in the treatment of chronic heart failure from the aspects of theoretical connotation,pathogenesis,pathophysiological relationship and modern research.In-depth study at the microscopic level demonstrated that the application of"reinforcing yang from yin"method can effectively improve the reconstruction of heart energy substrate(yin),enhance mitochondrial function,and finally provide energy support(yang),which could offer ideas for theoretical research and clinical prevention and treatment of chronic heart failure.关键词
慢性心力衰竭/阴中求阳/线粒体能量代谢Key words
chronic heart failure/reinforcing yang from yin/mitochondrial energy metabolism分类
中医学引用本文复制引用
王菲,钟森杰,李欣春,廉坤,李琳,胡志希..基于线粒体能量代谢探讨"阴中求阳"法治疗慢性心力衰竭科学内涵[J].中国中医药信息杂志,2024,31(1):6-10,5.基金项目
国家自然科学基金(82274412) (82274412)
广东省重点领域研发项目(2020B1111100001) (2020B1111100001)
湖南省自然科学基金面上项目(2020JJ4062) (2020JJ4062)
湖南省学位与研究生教育改革研究项目(2020JGZX012) (2020JGZX012)