中国中医药信息杂志2024，Vol.31Issue(1)：11-14,4.DOI:10.19879/j.cnki.1005-5304.202308347
从"虚气留滞夹火"探讨应激敏化所致抑郁症辨治思路
Exploration on Syndrome Differentiation Thinking for Stress Sensitization-induced Depression from the Perspective of"Deficient Qi with Stagnation and Heat"
摘要
Abstract
TCM proposes that the core pathological mechanism of depression is"deficient qi with stagnation and heat",with the following pathogenic characteristics and evolution patterns:"deficient qi"as the nature,and deficiency in nature is in spleen,and deficiency in superficiality is in brain;"stagnation"is the superficiality,and qi stagnation,phlegm stagnation,and blood stagnation are in the brain collaterals;"heat"fires the brain collaterals,depression raised the heat,and excessive heat accumulated to stagnation.Based on the understanding of the pathogenesis of depression caused by stress sensitization in modern medicine,this article explored the potential association between this mechanism and the core pathogenesis of"deficient qi with stagnation and heat".It proposed that tonifying deficiency,promoting circulation,and clearing heat are the basic treatment principles for depression.By inhibiting inflammatory reactions and improving the stress sensitization state of neurons and glial cells,TCM compound formulas can exert multi-target and multi-dimensional therapeutic characteristics.关键词
抑郁症/应激敏化/虚气留滞夹火/补虚通滞泻火Key words
depression/stress sensitization/deficient qi with stagnation and heat/tonifying deficiency,promoting circulation,and clearing heat分类
医药卫生引用本文复制引用
陈旭,曹竟,贾茜麟,郗凌云,白杨,庞浩宇,洪霞..从"虚气留滞夹火"探讨应激敏化所致抑郁症辨治思路[J].中国中医药信息杂志,2024,31(1):11-14,4.基金项目
中国中医科学院科技创新工程重大攻关项目(CI2021A01312) （CI2021A01312）
