内科2023，Vol.18Issue(6)：548-551,4.DOI:10.16121/j.cnki.cn45-1347/r.2023.06.08
以高蛋白饮食为基础的强化营养支持模式对晚期非小细胞肺癌合并恶性胸腔积液患者营养学指标与免疫功能的影响
Effect of the high-protein diet-based intensive nutritional support mode on nutritional indicators and immune function in patients with advanced non-small cell lung carcinoma and malignant hydrothorax
尚雪娇 1童真真 1郭娜娜1
作者信息
- 1. 河南省郑州市第三人民医院呼吸肿瘤内科,郑州市 450000
- 折叠
摘要
Abstract
Objective To investigate the effect of the high-protein diet-based intensive nutritional support mode on nutritional indicators and immune function in patients with advanced non-small cell lung carcinoma and malignant hydrothorax.Methods A total of 85 patients with advanced non-small cell lung carcinoma and malignant hydrothorax were selected as research objects and randomly divided into a control group(n=42)or an observation group(n=43).The control group was given standard dietary intervention,the observation group was given high-protein diet-based intensive nutritional support mode intervention,and both groups were intervened for 1 month.The nutritional indicators,immune function,and the incidence of complications were compared between the two groups.Results After 1 month of intervention,the serum prealbumin,hemoglobin,albumin levels;body mass index;serum CD3+,CD4+levels;and CD4+/CD8+in the observation group were higher than those in the control group(all P＜0.05).During the intervention,there was no statistically significant difference in the incidence of pleural reaction or pneumothorax between the two groups(all P＞0.05),and the incidence of malnutrition in the observation group was lower than that in the control group(P＜0.05).Conclusion The high-protein diet-based intensive nutritional support mode has a definite effect on patients with advanced non-small cell lung carcinoma and malignant hydrothorax,which can effectively improve patients'nutritional indicators,enhance their immune function,and reduce the incidence of malnutrition.关键词
晚期非小细胞肺癌/胸腔积液/高蛋白饮食/营养/免疫功能Key words
Advanced non-small cell lung carcinoma/Malignant hydrothorax/High-protein diet/Nutrition/Immune function分类
医药卫生引用本文复制引用
尚雪娇,童真真,郭娜娜..以高蛋白饮食为基础的强化营养支持模式对晚期非小细胞肺癌合并恶性胸腔积液患者营养学指标与免疫功能的影响[J].内科,2023,18(6):548-551,4.
