中国中医药信息杂志2024，Vol.31Issue(1)：44-50,7.DOI:10.19879/j.cnki.1005-5304.202212064
中医药调节miRNA研究文献可视化分析
Visualization Analysis on Research Literature of TCM Regulation of miRNA
摘要
Abstract
Objective To analyze the current status and trends of TCM regulation of microRNA(miRNA)using visualization methods.Methods The literature related to the TCM regulation of miRNA was retrieved from CNKI,VIP and Wanfang Data from the establishment of the databases to May 31,2022.Excel 2019,VOSviewer 1.6.18,and CiteSpace 5.8.R3 software were applied to visualize and analyze the year of publication,journal source,author and keywords of the included literature.Results A total of 787 articles were included,and the number of publications continued to rise.Source journals with more publications includes Chinese Journal of Experimental Traditional Medical Formulas,China Journal of Traditional Chinese Medicine and Pharmacy,Chinese Archives of Traditional Chinese Medicine,etc.Research teams were formed with Wang Jie,Liu Xide,Diao Limei,etc.as the representatives,and the cooperation among the teams was not very close.Analysis on the keywords in the literature showed that the studies mainly focused on apoptosis,miRNA-21,electroacupuncture,atherosclerosis,proliferation and other related fields;TCM intervention that accounted for the most research were extracts of Chinese materia medica,with 42%of the studies;there were 24 miRNAs studied≥3 times,and the most studied miRNA was miRNA-21.Conclusion The research hotspots of TCM regulation of miRNA are mainly the molecular mechanism of various TCM therapeutic tools to improve cell autophagy,apoptosis,inflammatory response and other pathways through regulation of miRNAs.The trend of research is to study the mechanism of empirical prescriptions of famous TCM practitioners based on precise therapeutic strategies.关键词
微小核糖核酸/CiteSpace/VOSviewer/可视化分析/中医药Key words
miRNA/CiteSpace/VOSviewer/visualization analysis/TCM分类
医药卫生引用本文复制引用
李伟青,王海东,李浩林,田雪梅,王爱华,苏小军,陈平,李向军..中医药调节miRNA研究文献可视化分析[J].中国中医药信息杂志,2024,31(1):44-50,7.基金项目
国家自然科学基金地区基金(82260880) （82260880）
甘肃省中医药项目(GZKP-2021-12) （GZKP-2021-12）
王海东甘肃省名中医传承工作室建设项目(2022年) （2022年）
