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小金丸联合祛瘀化痰消症汤治疗乳腺增生痰瘀互结证的临床效果

邵海洋 金根标

中国中西医结合外科杂志2023,Vol.29Issue(6):771-776,6.
中国中西医结合外科杂志2023,Vol.29Issue(6):771-776,6.DOI:10.3969/j.issn.1007-6948.2023.06.009

小金丸联合祛瘀化痰消症汤治疗乳腺增生痰瘀互结证的临床效果

Clinical study on Xiaojin pill combined with Quyu Huatan Xiaozheng decoction in treating hyperplasia of breast with phlegm-stasis syndrome

邵海洋 1金根标1

作者信息

  • 1. 绍兴市柯桥区中医医院普通外科(浙江绍兴 312030)
  • 折叠

摘要

Abstract

Objective To explore the curative effect of Xiaojin pill combined with Quyu Huatan Xiaozheng decoction in treating hyperplasia of mammary glands with phlegm and blood stasis.Methods 76 patients with breast hyperplasia who were treated in our hospital from July 2020 to July 2022 were selected as the research object.They were randomly divided into the observation group(38 cases)and the control group(38 cases).Both groups were treated with tamoxifen tablets,the control group with Xiaojin pills,and the observation group with Xiaojin pills combined with Quyu Huatan Xiaozheng decoction.After 6 weeks of treatment,the TCM syndrome score,estradiol(E2),prolactin(PRL),progesterone(P),breast blood flow resistance index,minimum blood flow velocity,maximum blood flow velocity,curative effect and adverse reaction rate of the two groups were compared.Results After treatment,the main and secondary syndrome scores of the two groups decreased,and the observation group was lower than the control group(P<0.05);PRL and E2 in the two groups were lower than those in the control group(P<0.05);P in both groups was higher than that in the control group(P<0.05);The blood flow resistance index of the two groups was lower than that of the control group(P<0.05);The minimum blood flow velocity and maximum blood flow velocity of the two groups were higher than those of the control group(P<0.05).The total effective rate of the observation group was higher than that of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P<0.05).Conclusion Xiaojin pill combined with Quyu Huatan Xiaozheng decoction can effectively regulate the sex hormone level of patients,improve the symptoms of traditional Chinese medicine,and regulate breast hemodynamics,with superior efficacy and good safety.

关键词

乳腺增生/痰瘀互结/小金丸/祛瘀化痰消症汤

Key words

Hyperplasia of mammary glands/phlegm and blood stasis/Xiaojin pill/Quyu Huatan Xiaozheng decoction

分类

医药卫生

引用本文复制引用

邵海洋,金根标..小金丸联合祛瘀化痰消症汤治疗乳腺增生痰瘀互结证的临床效果[J].中国中西医结合外科杂志,2023,29(6):771-776,6.

中国中西医结合外科杂志

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1007-6948

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