中国中西医结合外科杂志2023，Vol.29Issue(6)：793-797,5.DOI:10.3969/j.issn.1007-6948.2023.06.013
人参养荣汤对小细胞肺癌化疗后骨髓抑制患者疗效的影响
Effect of Ginseng Yangrong Decoction on the therapeutic effect of patients with bone marrow suppression after chemotherapy of small cell lung cancer
摘要
Abstract
Objective To explore the effect of Ginseng Yangrong Decoction on the curative effect of patients with bone marrow suppression after chemotherapy of small cell lung cancer.Methods A total of 120 patients with bone marrow suppression after chemotherapy for small cell lung cancer in our hospital from May 2019 to December 2020 were selected and randomly divided into a treatment group(60 cases)and a control group(60 cases)according to the random number table method.The control group was treated with western medicine,and the treatment group was treated with Ginseng Yangrong Decoction on the basis of the control group.The immune indicators[tumor necrosis factor-α(TNF-α),soluble interleukin-2 receptor(sIL-2R)],Karnofsky scale(KPS)and the MOS item short from health survey(SF-36)score,serum albumin level,white blood cell count,neutrophil count,platelet count,incidence of toxic and side effects and clinical efficacy were compared between the two groups.Results Compared with before treatment,after treatment,the KPS score,SF-36 score,TNF-α,serum albumin level,white blood cell count,neutrophil count,and platelet count of the two groups increased(P＜0.05),and the treatment group were higher than the control group(P＜0.05);the level of sIL-2R decreased(P＜0.05),and the treatment group was lower than the control group(P＜0.05).The incidence of side effects in the treatment group was 31.67％,and the incidence of side effects in the control group was 73.33％,in the treatment group was lower than the control group(P＜0.05);the total effective rate of the treatment group(76.67％)was higher than that of the control group(50.00％)(P＜0.05).Conclusion Ginseng Yangrong Decoction for patients with bone marrow suppression after chemotherapy for small cell lung cancer can improve the immune function and clinical symptoms of the patients,improve the quality of life,reduce the incidence of toxic and side effects,and enhance the efficacy.关键词
人参养荣汤/小细胞肺癌/化疗/骨髓抑制/白蛋白Key words
Ginseng Yangrong Decoction/small cell lung cancer/chemotherapy/bone marrow suppression/albumin分类
医药卫生引用本文复制引用
王振强,王洪亮,张庆江,陈晶晶,李小江,赵芳,赵阳,董雪珊,周雍明..人参养荣汤对小细胞肺癌化疗后骨髓抑制患者疗效的影响[J].中国中西医结合外科杂志,2023,29(6):793-797,5.基金项目
河北省中医药管理局课题(2017279) （2017279）
