中国医药科学2023，Vol.13Issue(23)：40-43,4.DOI:10.20116/j.issn2095-0616.2023.23.09
基于CiteSpace的微小RNA在脑缺血再灌注损伤中的研究现状及热点分析
Research status and hot spot analysis of CiteSpace-based microRNAs in cerebral ischemia-reperfusion injury
摘要
Abstract
Objective To summarize the research status and development trends of microRNAs related to cerebral ischemia-reperfusion injury(CIRI).Methods The relevant literature on microRNAs in CIRI from the core databases of China National Knowledge Infrastructure(CNKI)and Web of Science(WoS)was retrieved,and the CiteSpace 5.8.R3 software was applied for visual analysis of research authors,institutions,and keywords.Results A total of 165 Chinese articles and 433 English articles were included.Keyword analysis showed that apoptosis,oxidative stress,autophagy,and inflammation were the main mechanisms of action explored;Research interventions mainly focused on acupuncture and electroacupuncture,and basic research and review were the main forms of literature.Conclusion The study of microRNA provides relevant targets and more therapeutic possibilities for the improvement of CIRI,but it is still in the development stage.Therefore,it is necessary to strengthen cross-team and cross-regional cooperation among authors and institutions,and further in-depth research is needed to provide strong references for clarifying the relevant mechanisms of microRNA in CIRI.关键词
microRNA/脑缺血再灌注损伤/脑缺血/可视化分析/细胞凋亡Key words
microRNA/Cerebral ischemia-reperfusion injury/Cerebral ischemia/Visual analysis/Cell apoptosi分类
临床医学引用本文复制引用
罗亚男,李景炜,李若冰,梅志刚..基于CiteSpace的微小RNA在脑缺血再灌注损伤中的研究现状及热点分析[J].中国医药科学,2023,13(23):40-43,4.基金项目
湖北省科学技术厅自然科学基金一般青年项目(Z2022338) （Z2022338）
湖北省教育厅科学技术研究计划指导性项目(Z2020098) （Z2020098）
湖北省教育厅优秀中青年科技创新团队计划项目(Z2022266). （Z2022266）
