中国中医药信息杂志2024，Vol.31Issue(1)：185-190,6.DOI:10.19879/j.cnki.1005-5304.202211781
中医药改善慢性鼻窦炎内镜术后鼻黏膜重塑研究进展
Research Progress in TCM for the Improvement of Nasal Mucosa Remodeling after Endoscopy in Chronic Sinusitis
摘要
Abstract
TCM for the improvement of nasal mucosa remodeling after chronic sinusitis endoscopy is the key to the effective prevention of new lesions and recurrence in the surgical cavity mucosa.This article reviewed the mechanism of the nasal mucosa remodeling phenomenon after chronic sinusitis endoscopy and the unique advantages of TCM treatment.Deficiency,phlegm and blood stasis leading to"lung loss"is the perennial root of nasal mucosa remodeling.The treatment is"tonifying deficiency and removing phlegm,invigorating qi and promoting blood circulation",using acupuncture and medicine,and both internal and external treatment to regulate Th17/Treg balance and reduce the inflammatory infiltration;blocking the phosphorylation of MAPK and NF-κB pathway to inhibit TGF-β1-induced myofibroblasts,reduce collagen deposition and inhibit their remodeling,and promote the process of mucosal epithelialization,which can provide ideas for the theoretical and clinical treatment of TCM prevention and treatment of nasal mucosa remodeling.关键词
鼻窦炎/鼻黏膜重塑/炎症/免疫/黏膜上皮化/中医药/综述Key words
sinusitis/nasal mucosa remodeling/inflammation/immunity/mucosal epithelialization/TCM/review分类
医药卫生引用本文复制引用
刘继玲,周凌,姚旭涛,吴焱..中医药改善慢性鼻窦炎内镜术后鼻黏膜重塑研究进展[J].中国中医药信息杂志,2024,31(1):185-190,6.基金项目
国家自然科学基金面上项目(81874495) （81874495）
周凌全国名老中医药专家传承工作室建设项目(2022年) （2022年）
