中国现代医生2024，Vol.62Issue(1)：28-31,4.DOI:10.3969/j.issn.1673-9701.2024.01.007
光谱熵评价缺血性脑卒中患者镇痛镇静治疗效果的研究
Spectral entropy to evaluate the effectiveness of analgesic sedation in patients with ischaemic stroke
摘要
Abstract
Objective To investigate the reliability and feasibility of spectral entropy in evaluate the effectiveness of analgesic sedation in patients with ischemic stroke.Methods A total of 64 patients with acute ischemic stroke admitted to Hongqi Hospital Affiliated to Mudanjiang Medical University from July 2021 to November 2022 were selected as study objects,and the included patients were divided into control group and experimental group according to random number table method,with 32 cases in each group.Patients in control group adjusted analgesia and sedation regimen according to Richmond agitation-sedation scale(RASS)score and critical-care pain observation tool(CPOT)score.Patients in experimental group adjusted the analgesic and sedation regimen according to the results of spectral entropy.The vital signs,C-reactive protein(CRP),dose of sedative and analgesic drugs and incidence of adverse reactions were compared between two groups.The correlation between spectral entropy and RASS score and CPOT score was used Spearman correlation analysis.Results The spectral entropy values were positively correlated with the RASS score and CPOT score,respectively(r=0.719,0.556,P<0.001).There were no significant differences in mean arterial pressure and percutaneous arterial oxygen saturation between two groups at different time points(P>0.05).The heart rate at T3 in experimental group was significantly lower than that in control group(P<0.05).At T1,T2 and T3,CRP levels in experimental group were significantly lower than those in control group(P<0.05).The dosage of sufentanil and midazolam in experimental group were significantly lower than those in control group(P<0.05).The incidence of adverse reactions in experimental group was significantly lower than that in control group(12.50%vs.34.38%,χ2=4.267,P=0.039).Conclusion Spectral entropy can be used as an objective method to monitor the depth of analgesia and sedation in patients with ischemic stroke,and has a good correlation with RASS score and CPOT score,which can reduce the incidence of adverse reactions,effectively avoid stress reactions,and reduce the application of analgesia and sedation drugs.关键词
光谱熵/缺血性脑卒中/镇痛/镇静Key words
Spectral entropy/Ischemic stroke/Analgesia/Sedation分类
医药卫生引用本文复制引用
刘成仁,谢凤杰,郭永波,崔轮盟,李婉玉..光谱熵评价缺血性脑卒中患者镇痛镇静治疗效果的研究[J].中国现代医生,2024,62(1):28-31,4.基金项目
黑龙江省牡丹江市应用科技研究与开发计划项目(HT2022NS108) （HT2022NS108）
