浙江医学2023，Vol.45Issue(23)：2509-2512,2530,5.DOI:10.12056/j.issn.1006-2785.2023.45.23.2023-1450
超重及肥胖患者行无痛支气管镜检查时最佳氧流量的研究
Optimal oxygen flow in sedated bronchoscopy for overweight and obese patients
摘要
Abstract
Objective To determine the optimal oxygen flow of the high flow nasal cannula(HFNC)in sedated bronchoscopy for overweight and obese patients.Methods Sixty patients with BMI≥25 kg/m2 who underwent sedated bronchoscopy in Zhejiang Cancer Hospital from April to September 2022 were enrolled.Demographic information and past medical history(including snoring history)of the patients were collected,and the STOP-Bang questionnaire was also completed.Patients were randomly divided into six groups with 10 cases in each group,and different oxygen flow(10,20,30,40,50,60 L/min)was given during sedated bronchoscopy.Sufentanil and propofol were administered to maintain sedation,the incidence of hypoxemia and the need for airway intervention during bronchoscopy was recorded.Results With the increase of oxygen flow,the incidence of hypoxemia decreased from 60.0％to 40.0％,30.0％,30.0％,10.0％and 0 in 6 groups(P＜0.01),respectively.The incidence of jaw thrust maneuvers and requirement for increased oxygen flow decreased significantly with increasing oxygen flow rates(both P＜0.01),while the incidence of bag-mask ventilation had no significant difference(P＞0.05).Probit regression showed that the effective flow(EF90)was 49.9 L/min(95％CI:38.9-86.2 L/min)and EF95 was 59.2 L/min(95％CI:45.6-109.8 L/min).Conclusion With the increase of oxygen flow,the incidence of hypoxemia and the need for airway intervention in overweight and obese patients undergoing sedated bronchoscopy is decreased significantly,and an oxygen flow rate more than 50 L/min is suggested for the airway management.关键词
支气管镜/低氧血症/经鼻高流量氧疗Key words
Bronchoscopy/Hypoxemia/High flow nasal cannula引用本文复制引用
张雯,王江玲,方军,解康杰..超重及肥胖患者行无痛支气管镜检查时最佳氧流量的研究[J].浙江医学,2023,45(23):2509-2512,2530,5.基金项目
浙江省卫生健康科技计划项目(2021KY546) （2021KY546）
