中国当代医药2023，Vol.30Issue(36)：37-40,4.
结直肠管状腺瘤的危险因素分析
Analysis of risk factors for colorectal tubular adenoma
摘要
Abstract
Objective To explore the risk factors for colorectal tubular adenoma.Methods A total of 155 study subjects di-agnosed and treated at Linyi People's Hospital from January 2020 to December 2022 were selected as research objects,they were divided into two groups based on the results of colonoscopy observation and histopathological examination.Among them,77 patients with colorectal tubular adenoma were selected as the experimental group,and 78 patients without polyps under colonoscopy were selected as the control group.History of colorectal cancer in first-degree relatives,smoking history,history of alcohol consumption,age,gender,blood pressure,body mass index,fasting plasma glucose and blood lipids of two groups were compared.The risk factors for the occurrence of colorectal tubular adenoma were analyzed by using multivariate logistic regression.Results The smoking history,alcohol consumption history,history of colorectal cancer in first-degree relatives,triglycerides,high-density lipoprotein and fasting plasma glucose between two groups were compared,the differ-ences were statistically significant(P＜0.05).Fasting plasma glucose(β=0.747,OR=2.110,95%CI=1.389-3.206),triglyc-erides(β=1.513,OR=4.539,95%CI=2.119-9.719),history of colorectal cancer in first-degree relatives(β=1.529,OR= 4.615,95%CI=1.248-17.072),history of alcohol consumption(β=1.120,OR=3.064,95%CI=1.273-7.377)and smoking history(β=0.941,OR=2.564,95%CI=1.265-5.196)were risk factors for colorectal tubular adenoma(P＜0.05),and high-density lipoprotein(β=-1.095,OR=0.334,95%CI=0.117-0.954)was a protective factor for colorectal tubular adeno-ma(P＜0.05).Conclusion The occurrence of colorectal tubular adenoma is influenced by multiple factors,including elevat-ed fasting plasma glucose,elevated triglycerides,history of colorectal cancer in first-degree relatives,history of alcohol con-sumption and smoking history,which are independent risk factors,and high-density lipoprotein is a protective factor.关键词
管状腺瘤/危险因素/空腹血糖/甘油三酯Key words
Tubular adenoma/Risk factors/Fasting plasma glucose/Triglyceride分类
医药卫生引用本文复制引用
王明坤,时登娟,张倩文,曾雨桥,王立坤..结直肠管状腺瘤的危险因素分析[J].中国当代医药,2023,30(36):37-40,4.基金项目
山东省自然科学基金项目(ZR2021MH375) （ZR2021MH375）
山东省中医药科技重点项目(Z-2022036). （Z-2022036）
