检验医学与临床2024，Vol.21Issue(1)：20-23,4.DOI:10.3969/j.issn.1672-9455.2024.01.005
LMR与老年原发性高血压患者焦虑的关系研究
Relationship between LMR and anxiety in elderly patients with essential hypertension
摘要
Abstract
Objective To explore the relationship between the lymphocyte count/monocyte count ratio(LMR)and anxiety in elderly patients with essential hypertension(EH).Methods The basic data and labora-tory detection indicators of 197 patients with EH aged ≥60 years old hospitalized in the department of cardio-vascular medicine in this hospital from July 2020 to December 2021 were collected.With the Hamilton Anxie-ty Scale(HAMA)score ≥14 points as the critical value,the patients were divided into the anxiety group and non-anxiety group,and the differences in the basic data,LMR and other indicators at admission were compared between the two groups.The binary Logistic regression analysis was used to explore the influencing factors of anxiety state occurrence in the elderly patients with EH.The receiver operating characteristic(ROC)curve was adopted to analyze the predictive value of LMR for the anxiety occurrence in the elderly patients with EH.Results There were statistical differences in the drinking history,smoking history and LMR between the two groups(P＜0.05).The binary Logistic regression analysis results showed that LMR(OR=1.742,95％CI:1.414-2.146,P＜0.01)was an independent risk factor for the anxiety occurrence in the elderly pa-tients with EH.The ROC curve analysis results showed that the area under the curve(AUC)of LMR for pre-dicting the anxiety occurrence in elderly EH patients was 0.803(95％CI:0.740-0.866,P＜0.001),and the optimal cut-off value was 4.52,at this point,the sensitivity and specificity were 0.71 and 0.84,respectively.Conclusion Elevated level of LMR is an independent risk factor for the anxiety occurrence in the elderly EH patients and LMR has good predictive value for the anxiety occurrence in the elderly patients with EH.关键词
原发性高血压/焦虑/淋巴细胞计数与单核细胞计数比值/危险因素Key words
essential hypertension/anxiety/lymphocyte count/monocyte count ratio/risk factors分类
医药卫生引用本文复制引用
陈余文,王悦,李冰清,李册兴,李文倩,万少枝,孙培媛,吕建峰..LMR与老年原发性高血压患者焦虑的关系研究[J].检验医学与临床,2024,21(1):20-23,4.基金项目
湖北省卫生健康委员会课题(WJ2021F061). （WJ2021F061）
