PICCO监护联合床旁即时超声对ICU老年急性心力衰竭患者血气、血流动力学指标的影响及临床效能分析OACSTPCD
Effect of PICCO monitoring combined with bedside real-time ultrasound on blood gas and hemodynamics indexes in elderly patients with acute heart failure in ICU and clinical efficacy analysis
目的 探究脉搏轮廓温度稀释连续心排量测量(PICCO)监护联合床旁即时超声对重症监护室(ICU)老年急性心力衰竭患者血气、血流动力学指标的影响及临床效能.方法 选取2020年12月至2022年12月铜川市人民医院的150例老年急性心力衰竭患者为研究对象,按照采用的监测方式不同分为对照组和观察组,各75例.对照组常规应用PICCO监护,观察组在对照组的基础上额外应用床旁即时超声监测,两组均连续接受治疗72 h.比较两组治疗前后血清学指标、凝血情况、血气指标、血流动力学、心功能指标及临床效能情况.结果 治疗后,两组患者的血清钠尿肽(BNP)、肌钙蛋白I(TnI)、胱抑素C(CysC)、C反应蛋白(CRP)均显著改善,观察组患者BNP、TnI、CysC、CRP水平较对照组更低(P<0.05).治疗后,两组患者的氧合指数、动脉氧分压(PaO2)、中心静脉血氧饱和度(ScVO2)均显著提升(P<0.05),两组中心静脉压(CVP)比较,差异无统计学意义(P>0.05),但观察组患者的氧合指数、PaO2、ScVO2较对照组更高(P<0.05).治疗后,两组患者的心脏指数(CI)、心排血量(CO)、每搏量(SV)均明显升高,全心舒张末期容积指数(GEDI)、全身血管阻力指数(SVRI)明显下降,且观察组CI、CO、SV高于对照组,GEDI、SVRI低于对照组,差异均有统计学意义(P<0.05).治疗后两组患者的活化部分凝血活酶时间(APTT)、凝血酶时间(TT)缩短,D-二聚体(D-D)水平降低(P<0.05),且观察组缩短/降低程度更高(P<0.05).观察组患者的ICU内心力衰竭复发率、机器通气时间、ICU住院时间、治疗方案更改率均优于低于对照组(P<0.05),两组30 d内病死率比较,差异无统计学意义(P>0.05).结论 ICU老年急性心力衰竭患者应用床旁即时超声联合PICCO监护有较好的临床监测效能,能够更好地改善患者的血气、血流动力学和心功能指标,降低治疗方案的更改频率.
Objective To investigate the effects of continuous pulse profile temperature dilution cardiac displacement measurement(PICCO)monitoring combined with bedside real-time ultrasound on the blood gas and hemodynamic indexes in elderly patients with acute heart failure in intensive care unit(ICU)and its clini-cal efficacy.Methods One hundred and fifty elderly patients with acute heart failure in Tongchuan Municipal People's Hospital from December 2020 to December 2022 were selected as the study subjects and divided into the control group and observation group according to different monitoring methods,75 cases in each group.The control group routinely used PICCO monitoring,and the observation group additionally used the bedside real-time ultrasound monitoring on the basis of the control group.Both groups received the continuous treat-ment for 72 h.Serum indexes,coagulation situation,blood gas indexes,hemodynamic and cardiac function in-dexes and clinical efficacy before and after treatment were compared between the two groups.Results Serum natriuretic peptides(BNP),troponin I(TnI),Cystatin C(CysC),C-reactive protein(CRP)levels after treat-ment were significantly improved,in which the levels of BNP,TnI,CysC and CRP in the observation group were lower than those in the control group(P<0.05).After treatment,the oxygenation index,arterial oxygen pressure(PaO2)and central venous oxygen saturation(ScVO2)in the two groups were significantly increased(P<0.05),and there was no statistically significant difference in the central venous pressure(CVP)between the two groups(P>0.05).However,the oxygenation index,PaO2 and ScVO2 in the observation group were higher than those in the control group(P<0.05).After treatment,the cardiac index(CI),cardiac output(CO)and stroke volume(SV)levels in the two groups were significantly increased,while the global end-dias-tolic volume index(GEDI)and systemic vascular resistance index(SVRI)levels were significantly decreased,moreover the CI,CO and SV levels in the observation group were higher than those in the control group,while the GEDI and SVRI levels were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the activated partial thromboplatin time(APTT),thrombin time(TT)and D-Dimer(D-D)levels were in the two groups were reduced(P<0.05),moreover the shortening/decreasing degree in the observation group was higher(P<0.05).The recurrence rate of heart failure in ICU,machinery ventilation time,ICU stay time and change rate of treatment regimen in the observation group were better than those in the control group(P<0.05),and there was no statistically significant difference in the mortality within 30 d between the two groups(P>0.05).Conclusion The bedside real-time ultrasound com-bined with PICCO monitoring for elderly patients with acute heart failure in ICU has better clinical monitoring efficacy,can better improve the blood gas,hemodynamic and cardiac function indexes of the patients,and re-duce the frequency of change of treatment regimen.
王青霞;赵丽丽;申丁丁;方婷
陕西省铜川市人民医院呼吸与危重症医学科,陕西铜川 727000陕西省靖边县人民医院心内科,陕西榆林 718500
临床医学
脉搏轮廓温度稀释连续心排量测量床旁即时超声急性心力衰竭血流动力学血气指标
continuous pulse profile temperature dilution cardiac displacement measurementbedside re-al-time ultrasoundacute heart failurehemodynamicsblood gas index
《检验医学与临床》 2024 (001)
107-112 / 6
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